FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2057810132> ?p ?o ?g. }

• W2057810132 endingPage "2928" @default.
• W2057810132 startingPage "2921" @default.
• W2057810132 abstract "Cardiac stem cells are vulnerable to inflammation caused by infarction or ischemic injury. The growth factor, erythropoietin (Epo), ameliorates the inflammatory response of the myocardium to ischemic injury. This study was designed to assess the role of Epo in regulation of expression and activation of the cell death-associated intracellular signaling components in cardiac myoblasts stimulated with the proinflammatory cytokine tumor necrosis factor (TNF)-alpha. Cardiac myoblasts isolated from canine embryonic hearts characterized by expression of myocardin A, a promyogenic transcription factor for cardiovascular muscle development were pretreated with Epo and then exposed to TNF-alpha. Compared to untreated cells, the Epo-treated cardiac myoblasts exhibited better morphology and viability. Immunoblotting revealed lower levels of active caspase-3 and reductions in iNOS expression and NO production in Epo-treated cells. Furthermore, Epo pretreatment reduced nuclear translocation of NF-kappaB and inhibited phosphorylation of inhibitor of kappa B (IkappaB) in TNF-alpha-stimulated cardiac myoblasts. Thus, Epo protects cardiac myocyte progenitors or myoblasts against the cytotoxic effects of TNF-alpha by inhibiting NF-kappaB-mediated iNOS expression and NO production and by preventing caspase-3 activation." @default.
• W2057810132 created "2016-06-24" @default.
• W2057810132 creator A5013180336 @default.
• W2057810132 creator A5038346349 @default.
• W2057810132 creator A5045515686 @default.
• W2057810132 creator A5067302152 @default.
• W2057810132 creator A5079077062 @default.
• W2057810132 creator A5086762809 @default.
• W2057810132 date "2009-10-01" @default.
• W2057810132 modified "2023-09-27" @default.
• W2057810132 title "Erythropoietin protects myocardin-expressing cardiac stem cells against cytotoxicity of tumor necrosis factor-α" @default.
• W2057810132 cites W1591881963 @default.
• W2057810132 cites W1969127451 @default.
• W2057810132 cites W1969447614 @default.
• W2057810132 cites W1978726693 @default.
• W2057810132 cites W1998581885 @default.
• W2057810132 cites W1999890296 @default.
• W2057810132 cites W2002189627 @default.
• W2057810132 cites W2005450615 @default.
• W2057810132 cites W2005495277 @default.
• W2057810132 cites W2007327939 @default.
• W2057810132 cites W2013995972 @default.
• W2057810132 cites W2035968568 @default.
• W2057810132 cites W2050602931 @default.
• W2057810132 cites W2058141781 @default.
• W2057810132 cites W2062205148 @default.
• W2057810132 cites W2069601655 @default.
• W2057810132 cites W2079527824 @default.
• W2057810132 cites W2101759139 @default.
• W2057810132 cites W2105197388 @default.
• W2057810132 cites W2106292297 @default.
• W2057810132 cites W2108712459 @default.
• W2057810132 cites W2110042016 @default.
• W2057810132 cites W2113175417 @default.
• W2057810132 cites W2117207344 @default.
• W2057810132 cites W2129932871 @default.
• W2057810132 cites W2154818940 @default.
• W2057810132 cites W2157312122 @default.
• W2057810132 cites W2158139135 @default.
• W2057810132 cites W2189490179 @default.
• W2057810132 cites W2328511175 @default.
• W2057810132 doi "https://doi.org/10.1016/j.yexcr.2009.07.016" @default.
• W2057810132 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19631208" @default.
• W2057810132 hasPublicationYear "2009" @default.
• W2057810132 type Work @default.
• W2057810132 sameAs 2057810132 @default.
• W2057810132 citedByCount "16" @default.
• W2057810132 countsByYear W20578101322012 @default.
• W2057810132 countsByYear W20578101322013 @default.
• W2057810132 countsByYear W20578101322014 @default.
• W2057810132 countsByYear W20578101322020 @default.
• W2057810132 countsByYear W20578101322021 @default.
• W2057810132 countsByYear W20578101322023 @default.
• W2057810132 crossrefType "journal-article" @default.
• W2057810132 hasAuthorship W2057810132A5013180336 @default.
• W2057810132 hasAuthorship W2057810132A5038346349 @default.
• W2057810132 hasAuthorship W2057810132A5045515686 @default.
• W2057810132 hasAuthorship W2057810132A5067302152 @default.
• W2057810132 hasAuthorship W2057810132A5079077062 @default.
• W2057810132 hasAuthorship W2057810132A5086762809 @default.
• W2057810132 hasConcept C104317684 @default.
• W2057810132 hasConcept C126322002 @default.
• W2057810132 hasConcept C134018914 @default.
• W2057810132 hasConcept C164027704 @default.
• W2057810132 hasConcept C17991360 @default.
• W2057810132 hasConcept C203014093 @default.
• W2057810132 hasConcept C207200792 @default.
• W2057810132 hasConcept C2776914184 @default.
• W2057810132 hasConcept C2778534260 @default.
• W2057810132 hasConcept C2780286377 @default.
• W2057810132 hasConcept C502942594 @default.
• W2057810132 hasConcept C55493867 @default.
• W2057810132 hasConcept C69053785 @default.
• W2057810132 hasConcept C71924100 @default.
• W2057810132 hasConcept C86339819 @default.
• W2057810132 hasConcept C86803240 @default.
• W2057810132 hasConceptScore W2057810132C104317684 @default.
• W2057810132 hasConceptScore W2057810132C126322002 @default.
• W2057810132 hasConceptScore W2057810132C134018914 @default.
• W2057810132 hasConceptScore W2057810132C164027704 @default.
• W2057810132 hasConceptScore W2057810132C17991360 @default.
• W2057810132 hasConceptScore W2057810132C203014093 @default.
• W2057810132 hasConceptScore W2057810132C207200792 @default.
• W2057810132 hasConceptScore W2057810132C2776914184 @default.
• W2057810132 hasConceptScore W2057810132C2778534260 @default.
• W2057810132 hasConceptScore W2057810132C2780286377 @default.
• W2057810132 hasConceptScore W2057810132C502942594 @default.
• W2057810132 hasConceptScore W2057810132C55493867 @default.
• W2057810132 hasConceptScore W2057810132C69053785 @default.
• W2057810132 hasConceptScore W2057810132C71924100 @default.
• W2057810132 hasConceptScore W2057810132C86339819 @default.
• W2057810132 hasConceptScore W2057810132C86803240 @default.
• W2057810132 hasIssue "17" @default.
• W2057810132 hasLocation W20578101321 @default.
• W2057810132 hasLocation W20578101322 @default.
• W2057810132 hasOpenAccess W2057810132 @default.
• W2057810132 hasPrimaryLocation W20578101321 @default.
• W2057810132 hasRelatedWork W1990717759 @default.

• next