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• W2057822012 abstract "The Sec6/8 complex is essential for specific exocytic sites on the plasma membrane and contributes to membrane growth in mammalian cells. In Madin-Darby canine kidney (MDCK) cells, E-cadherin and nectin-based adhesion complexes recruit the Sec6/8 complex to intercellular contacts. However, in cancer cells, the relationship between the Sec6/8 complex and the cell–cell adhesion proteins remains obscure. We demonstrate that the expression of α-E-catenin is increased by Sec6 siRNAs, and E-cadherin and β-catenin localize mainly at the cell–cell contact region in HSC3 cells, which were transfected with Sec6 siRNA." @default.
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• W2057822012 date "2012-02-24" @default.
• W2057822012 modified "2023-10-03" @default.
• W2057822012 title "Knockdown of Sec6 improves cell-cell adhesion by increasing α-E-catenin in oral cancer cells" @default.
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• W2057822012 doi "https://doi.org/10.1016/j.febslet.2012.02.026" @default.
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