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- W2057862437 abstract "In cardiology, our ability to cure is rare. When cardiac disease is diagnosed, most of our treatments are palliative. They may remove or diminish complaints and prolong life but usually will not be able to stop the disease process. Cure is possible, however, in the patient suffering from a tachycardia in an otherwise normal heart. In that patient, we can locate the site of abnormal impulse formation or a critical part of the tachycardia pathway by cardiac activation mapping during the arrhythmia. Through the same or another catheter, radiofrequency (RF) energy can be applied to that area, resulting in destruction of a few millimeters of critical tissue and cure of the patient. That technique has been with us now for a decade.1 2 3 4 During that decade, RF energy applied through a catheter has been shown to be very effective in different types of supraventricular tachycardia.A method can be effective, but its use may be limited because of complications. The key question, therefore, is, how safe is RF catheter ablation in the treatment of patients with arrhythmias? Certain risks are associated with RF ablation. They include the general risks of any cardiac catheterization, such as thromboembolic complications, infection, bleeding, cardiac perforation with or without cardiac tamponade, valvular damage, and radiation damage. In addition, specific risks are related to the ablation procedure itself.To abolish the substrate of an arrhythmia, a small area of myocardial necrosis is necessary. It is difficult, however, to assess in vivo the amount of tissue destroyed by RF ablation. Several investigators have looked at the value of biochemical markers to estimate the amount of myocardial necrosis after ablation. Haines et al5 showed that measurement of the creatine activity significantly underestimated the volume of myocardial injury because creatine kinase (CK) activity is not …" @default.
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- W2057862437 title "Catheter Ablation of Cardiac Arrhythmias" @default.
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- W2057862437 doi "https://doi.org/10.1161/01.cir.99.2.195" @default.
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