FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2057865928> ?p ?o ?g. }

• W2057865928 abstract "The importance of slow-wave sleep (SWS), hallmarked by the occurrence of sleep slow oscillations (SO), for the consolidation of hippocampus-dependent memories has been shown. Previously, the application of transcranial direct current stimulation, oscillating at the frequency of endogenous slow oscillations, during SWS enhanced memory consolidation for a hippocampus dependent task in human subjects and suggested a causal role of SOs for sleep dependent memory consolidation ( Marshall et al., 2006 ). Objectives We aimed to replicate and extend these findings to a rodent model. Methods Slow oscillatory direct transcranial current stimulation (so-tDCS) was applied over the frontal cortex of rats during slow-wave sleep (SWS) and its effects on memory consolidation in the one-trial object-place recognition task (OPR) were examined. The OPR is a spatial memory task, and has been shown to depend critically on intact hippocampal function ( [Bussey et al., 2000] , [Mumby et al., 2002] ). It does not involve stressful procedures or food deprivation; it is based on the rodents’ natural behavior, i.e., novelty preference ( Ennaceur et al., 1997 ) and allows for intra-subject testing for stimulation and sham conditions. Previous findings showed the dependency of this task on sleep containing a large amount of slow wave activity within the retention interval ( [Binder et al., 2012] , [Inostroza et al., 2012] ). In a within subject design, 12 rats received one so-tDCS over the frontal cortex and one sham-tDCS session immediately after learning during early SWS. 24 h after learning, the test session in the OPR task took place to investigate the effects of so-tDCS on long-term memory. Results As depicted in Fig. 1 , animals were only able to solve the task following so-tDCS, but failed to do so in the sham condition lacking so-tDCS. EEG spectral power indicated a transitory enhancement of endogenous SO activity after cessation of so-tDCS. Conclusion We conclude that SO play a causal role for sleep dependent memory consolidation, and state that oscillatory tDCS is a highly valuable tool to further investigate the function of endogenous cortical network activity." @default.
• W2057865928 created "2016-06-24" @default.
• W2057865928 creator A5027996373 @default.
• W2057865928 creator A5039759164 @default.
• W2057865928 creator A5043532295 @default.
• W2057865928 creator A5044107804 @default.
• W2057865928 creator A5073905698 @default.
• W2057865928 date "2013-10-01" @default.
• W2057865928 modified "2023-09-26" @default.
• W2057865928 title "OP 1. Boosting sleep slow oscillations by oscillatory transcranial direct current stimulation enhances memory consolidation in rats" @default.
• W2057865928 cites W1975136983 @default.
• W2057865928 cites W2010258110 @default.
• W2057865928 cites W2011714236 @default.
• W2057865928 cites W2024032885 @default.
• W2057865928 cites W2059215368 @default.
• W2057865928 cites W2138602729 @default.
• W2057865928 doi "https://doi.org/10.1016/j.clinph.2013.04.068" @default.
• W2057865928 hasPublicationYear "2013" @default.
• W2057865928 type Work @default.
• W2057865928 sameAs 2057865928 @default.
• W2057865928 citedByCount "0" @default.
• W2057865928 crossrefType "journal-article" @default.
• W2057865928 hasAuthorship W2057865928A5027996373 @default.
• W2057865928 hasAuthorship W2057865928A5039759164 @default.
• W2057865928 hasAuthorship W2057865928A5043532295 @default.
• W2057865928 hasAuthorship W2057865928A5044107804 @default.
• W2057865928 hasAuthorship W2057865928A5073905698 @default.
• W2057865928 hasConcept C148762608 @default.
• W2057865928 hasConcept C15744967 @default.
• W2057865928 hasConcept C169760540 @default.
• W2057865928 hasConcept C24998067 @default.
• W2057865928 hasConcept C2777803708 @default.
• W2057865928 hasConcept C2778738651 @default.
• W2057865928 hasConcept C2781161787 @default.
• W2057865928 hasConcept C48455012 @default.
• W2057865928 hasConcept C548259974 @default.
• W2057865928 hasConcept C71924100 @default.
• W2057865928 hasConcept C77805123 @default.
• W2057865928 hasConceptScore W2057865928C148762608 @default.
• W2057865928 hasConceptScore W2057865928C15744967 @default.
• W2057865928 hasConceptScore W2057865928C169760540 @default.
• W2057865928 hasConceptScore W2057865928C24998067 @default.
• W2057865928 hasConceptScore W2057865928C2777803708 @default.
• W2057865928 hasConceptScore W2057865928C2778738651 @default.
• W2057865928 hasConceptScore W2057865928C2781161787 @default.
• W2057865928 hasConceptScore W2057865928C48455012 @default.
• W2057865928 hasConceptScore W2057865928C548259974 @default.
• W2057865928 hasConceptScore W2057865928C71924100 @default.
• W2057865928 hasConceptScore W2057865928C77805123 @default.
• W2057865928 hasLocation W20578659281 @default.
• W2057865928 hasOpenAccess W2057865928 @default.
• W2057865928 hasPrimaryLocation W20578659281 @default.
• W2057865928 hasRelatedWork W2076136875 @default.
• W2057865928 hasRelatedWork W2097201141 @default.
• W2057865928 hasRelatedWork W2112967992 @default.
• W2057865928 hasRelatedWork W2122509421 @default.
• W2057865928 hasRelatedWork W2135541601 @default.
• W2057865928 hasRelatedWork W2343960448 @default.
• W2057865928 hasRelatedWork W2472440797 @default.
• W2057865928 hasRelatedWork W2569055023 @default.
• W2057865928 hasRelatedWork W2588295652 @default.
• W2057865928 hasRelatedWork W2588802158 @default.
• W2057865928 hasRelatedWork W2589052260 @default.
• W2057865928 hasRelatedWork W2767884535 @default.
• W2057865928 hasRelatedWork W2782567892 @default.
• W2057865928 hasRelatedWork W2792437296 @default.
• W2057865928 hasRelatedWork W2888013372 @default.
• W2057865928 hasRelatedWork W2905182699 @default.
• W2057865928 hasRelatedWork W2916750922 @default.
• W2057865928 hasRelatedWork W3024088417 @default.
• W2057865928 hasRelatedWork W3136396748 @default.
• W2057865928 hasRelatedWork W3197514370 @default.
• W2057865928 isParatext "false" @default.
• W2057865928 isRetracted "false" @default.
• W2057865928 magId "2057865928" @default.
• W2057865928 workType "article" @default.