FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2057911682> ?p ?o ?g. }

• W2057911682 endingPage "534" @default.
• W2057911682 startingPage "528" @default.
• W2057911682 abstract "Umbilical cord haematopoietic stem cell transplantation for primary immunodeficiencies is examined with other developments in treatment. Cord blood biology is reviewed, and advantages and disadvantages of umbilical cord blood stem cell transplantation for primary immunodeficiencies discussed. Clinical outcome data and future developments are reviewed.Cord blood T lymphocytes become tolerant to host human leukocyte antigen antigens, but retain alloreactivity to other antigens, in part due to immaturity of cord blood T lymphocytes and dendritic cells. Although naïve T lymphocytes can generate herpes virus specificity after transplantation, the risk of viral death is increased within the first 100 days. The clinical success of umbilical cord blood stem cell transplantation for primary immunodeficiencies is reviewed and new methods for expanding the stem cell number or encouraging engraftment with the use of third-party haematopoietic or mesenchymal stem cells examined.Many advantages make umbilical cord blood an attractive source of stem cells; over 100 umbilical cord blood stem cell transplantations have been performed for primary immunodeficiencies, with low rates of significant graft vs. host disease, despite significant human leukocyte antigen mismatch. Immune reconstitution is as good as for other stem cell sources: use of nascent stem cells in young recipients may have long-term advantages. Stem cell engineering to improve engraftment will expand potential beneficiaries of umbilical cord blood stem cell transplantation to older patients." @default.
• W2057911682 created "2016-06-24" @default.
• W2057911682 creator A5013983797 @default.
• W2057911682 creator A5014990865 @default.
• W2057911682 date "2007-12-01" @default.
• W2057911682 modified "2023-10-18" @default.
• W2057911682 title "Cord blood stem cell transplantation in primary immune deficiencies" @default.
• W2057911682 cites W1750208981 @default.
• W2057911682 cites W1967431361 @default.
• W2057911682 cites W1968336299 @default.
• W2057911682 cites W1970788402 @default.
• W2057911682 cites W1970806674 @default.
• W2057911682 cites W1979069232 @default.
• W2057911682 cites W1984588501 @default.
• W2057911682 cites W1987696799 @default.
• W2057911682 cites W2002974562 @default.
• W2057911682 cites W2003730389 @default.
• W2057911682 cites W2004665427 @default.
• W2057911682 cites W2012650379 @default.
• W2057911682 cites W2012807631 @default.
• W2057911682 cites W2019396018 @default.
• W2057911682 cites W2020966746 @default.
• W2057911682 cites W2023775692 @default.
• W2057911682 cites W2024041171 @default.
• W2057911682 cites W2024927228 @default.
• W2057911682 cites W2025962847 @default.
• W2057911682 cites W2034192561 @default.
• W2057911682 cites W2036235673 @default.
• W2057911682 cites W2041713109 @default.
• W2057911682 cites W2047604240 @default.
• W2057911682 cites W2047736496 @default.
• W2057911682 cites W2048993178 @default.
• W2057911682 cites W2056250174 @default.
• W2057911682 cites W2062920658 @default.
• W2057911682 cites W2069209063 @default.
• W2057911682 cites W2072010940 @default.
• W2057911682 cites W2080636075 @default.
• W2057911682 cites W2082133405 @default.
• W2057911682 cites W2091583315 @default.
• W2057911682 cites W2091616648 @default.
• W2057911682 cites W2111120371 @default.
• W2057911682 cites W2111158359 @default.
• W2057911682 cites W2113288066 @default.
• W2057911682 cites W2131199757 @default.
• W2057911682 cites W2136590050 @default.
• W2057911682 cites W2139485932 @default.
• W2057911682 cites W2145671779 @default.
• W2057911682 cites W2147323639 @default.
• W2057911682 cites W2158302549 @default.
• W2057911682 cites W2164238434 @default.
• W2057911682 cites W2314034700 @default.
• W2057911682 cites W2322205184 @default.
• W2057911682 cites W2331876857 @default.
• W2057911682 cites W2333162405 @default.
• W2057911682 cites W2333694726 @default.
• W2057911682 cites W56665654 @default.
• W2057911682 doi "https://doi.org/10.1097/aci.0b013e3282f1d6b6" @default.
• W2057911682 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17989530" @default.
• W2057911682 hasPublicationYear "2007" @default.
• W2057911682 type Work @default.
• W2057911682 sameAs 2057911682 @default.
• W2057911682 citedByCount "21" @default.
• W2057911682 countsByYear W20579116822012 @default.
• W2057911682 countsByYear W20579116822013 @default.
• W2057911682 countsByYear W20579116822014 @default.
• W2057911682 countsByYear W20579116822015 @default.
• W2057911682 countsByYear W20579116822016 @default.
• W2057911682 countsByYear W20579116822017 @default.
• W2057911682 countsByYear W20579116822020 @default.
• W2057911682 crossrefType "journal-article" @default.
• W2057911682 hasAuthorship W2057911682A5013983797 @default.
• W2057911682 hasAuthorship W2057911682A5014990865 @default.
• W2057911682 hasConcept C109159458 @default.
• W2057911682 hasConcept C126322002 @default.
• W2057911682 hasConcept C147483822 @default.
• W2057911682 hasConcept C188280979 @default.
• W2057911682 hasConcept C203014093 @default.
• W2057911682 hasConcept C2776955114 @default.
• W2057911682 hasConcept C2777408962 @default.
• W2057911682 hasConcept C2780914630 @default.
• W2057911682 hasConcept C28328180 @default.
• W2057911682 hasConcept C2908824208 @default.
• W2057911682 hasConcept C2911091166 @default.
• W2057911682 hasConcept C71924100 @default.
• W2057911682 hasConcept C86803240 @default.
• W2057911682 hasConcept C8891405 @default.
• W2057911682 hasConcept C95444343 @default.
• W2057911682 hasConceptScore W2057911682C109159458 @default.
• W2057911682 hasConceptScore W2057911682C126322002 @default.
• W2057911682 hasConceptScore W2057911682C147483822 @default.
• W2057911682 hasConceptScore W2057911682C188280979 @default.
• W2057911682 hasConceptScore W2057911682C203014093 @default.
• W2057911682 hasConceptScore W2057911682C2776955114 @default.
• W2057911682 hasConceptScore W2057911682C2777408962 @default.
• W2057911682 hasConceptScore W2057911682C2780914630 @default.
• W2057911682 hasConceptScore W2057911682C28328180 @default.
• W2057911682 hasConceptScore W2057911682C2908824208 @default.
• W2057911682 hasConceptScore W2057911682C2911091166 @default.

• next