Matches in SemOpenAlex for { <https://semopenalex.org/work/W2057921110> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W2057921110 endingPage "208" @default.
- W2057921110 startingPage "203" @default.
- W2057921110 abstract "Eosinophils and their products are known to cause hyperreactivity and swelling of the nasal mucosa in subjects with nasal allergy. Interleukin-5 (IL-5) not only induces differentiation and proliferation of immature eosinophils but also causes mature cells to accumulate and activate. This study shows that IL-5 is actually produced in the human nasal mucosa by antigen challenge, and it further investigates the changes in the amount of IL-5 in nasal lavage fluids after antigen challenge. Expression of mRNA for IL-5 in nasal mucosa was investigated using the reverse transcription-polymerase chain reaction (RT-PCR) and Southern blot analysis. Among the 4 subjects with nasal allergy examined in this study, expression of mRNA for IL-5 was observed in 2 prior to antigen challenge; within 6 h after antigen challenge it was seen in 3 subjects. We also found that the amount of IL-5 in the nasal lavage fluids obtained consecutively after antigen challenge increased predominantly in the late phase, and that the number of eosinophils in the IL-5 positive group was significantly higher than that in the IL-5 negative group. These results strongly suggest that IL-5 contributes to the recruitment of eosinophils in the nasal mucosa of the subjects with nasal allergy." @default.
- W2057921110 created "2016-06-24" @default.
- W2057921110 creator A5010093485 @default.
- W2057921110 creator A5012556565 @default.
- W2057921110 creator A5013566870 @default.
- W2057921110 creator A5028395684 @default.
- W2057921110 creator A5033853031 @default.
- W2057921110 creator A5055891842 @default.
- W2057921110 creator A5072232523 @default.
- W2057921110 creator A5072767964 @default.
- W2057921110 date "1994-01-01" @default.
- W2057921110 modified "2023-09-26" @default.
- W2057921110 title "Interleukin-5 Gene Expression in Nasal Mucosa and Changes in Amount of Interleukin-5 in Nasal Lavage Fluid After Antigen Challenge" @default.
- W2057921110 cites W1519148488 @default.
- W2057921110 cites W1969060950 @default.
- W2057921110 cites W2017336448 @default.
- W2057921110 cites W2032118018 @default.
- W2057921110 cites W2060333964 @default.
- W2057921110 cites W2060543236 @default.
- W2057921110 cites W2073497478 @default.
- W2057921110 cites W2099109162 @default.
- W2057921110 cites W2129494035 @default.
- W2057921110 cites W2160572043 @default.
- W2057921110 cites W2253356656 @default.
- W2057921110 cites W2335044720 @default.
- W2057921110 cites W4244074181 @default.
- W2057921110 doi "https://doi.org/10.3109/00016489409126043" @default.
- W2057921110 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8203203" @default.
- W2057921110 hasPublicationYear "1994" @default.
- W2057921110 type Work @default.
- W2057921110 sameAs 2057921110 @default.
- W2057921110 citedByCount "23" @default.
- W2057921110 crossrefType "journal-article" @default.
- W2057921110 hasAuthorship W2057921110A5010093485 @default.
- W2057921110 hasAuthorship W2057921110A5012556565 @default.
- W2057921110 hasAuthorship W2057921110A5013566870 @default.
- W2057921110 hasAuthorship W2057921110A5028395684 @default.
- W2057921110 hasAuthorship W2057921110A5033853031 @default.
- W2057921110 hasAuthorship W2057921110A5055891842 @default.
- W2057921110 hasAuthorship W2057921110A5072232523 @default.
- W2057921110 hasAuthorship W2057921110A5072767964 @default.
- W2057921110 hasConcept C142724271 @default.
- W2057921110 hasConcept C147483822 @default.
- W2057921110 hasConcept C181901479 @default.
- W2057921110 hasConcept C203014093 @default.
- W2057921110 hasConcept C207480886 @default.
- W2057921110 hasConcept C2778690821 @default.
- W2057921110 hasConcept C2909203445 @default.
- W2057921110 hasConcept C2909814679 @default.
- W2057921110 hasConcept C59377437 @default.
- W2057921110 hasConcept C71924100 @default.
- W2057921110 hasConcept C74172505 @default.
- W2057921110 hasConceptScore W2057921110C142724271 @default.
- W2057921110 hasConceptScore W2057921110C147483822 @default.
- W2057921110 hasConceptScore W2057921110C181901479 @default.
- W2057921110 hasConceptScore W2057921110C203014093 @default.
- W2057921110 hasConceptScore W2057921110C207480886 @default.
- W2057921110 hasConceptScore W2057921110C2778690821 @default.
- W2057921110 hasConceptScore W2057921110C2909203445 @default.
- W2057921110 hasConceptScore W2057921110C2909814679 @default.
- W2057921110 hasConceptScore W2057921110C59377437 @default.
- W2057921110 hasConceptScore W2057921110C71924100 @default.
- W2057921110 hasConceptScore W2057921110C74172505 @default.
- W2057921110 hasIssue "2" @default.
- W2057921110 hasLocation W20579211101 @default.
- W2057921110 hasLocation W20579211102 @default.
- W2057921110 hasOpenAccess W2057921110 @default.
- W2057921110 hasPrimaryLocation W20579211101 @default.
- W2057921110 hasRelatedWork W2000901676 @default.
- W2057921110 hasRelatedWork W2008282176 @default.
- W2057921110 hasRelatedWork W2011069185 @default.
- W2057921110 hasRelatedWork W2057921110 @default.
- W2057921110 hasRelatedWork W2068384475 @default.
- W2057921110 hasRelatedWork W2157547519 @default.
- W2057921110 hasRelatedWork W2329430828 @default.
- W2057921110 hasRelatedWork W2397292518 @default.
- W2057921110 hasRelatedWork W2398488307 @default.
- W2057921110 hasRelatedWork W2419129248 @default.
- W2057921110 hasVolume "114" @default.
- W2057921110 isParatext "false" @default.
- W2057921110 isRetracted "false" @default.
- W2057921110 magId "2057921110" @default.
- W2057921110 workType "article" @default.