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- W2057930062 abstract "Traditionally, dense amnesia in humans has been thought to be caused by damage to memory structures within the medial temporal lobe, either the hippocampus, the perirhinal cortex or a combination of the two. Recent work in animals has indicated that damage to the hippocampus results in memory impairments that are specific to memories for events. In contrast, damage to the perirhinal cortex impairs object memories in primates, which are likely to be analogous to human semantic memory. Discrete damage to either of these structures does not appear to result in severe and global memory impairments. We propose an alternative to this medial temporal lobe explanation of dense amnesia, based on our recent work. We have shown that the cholinergic cells of the basal forebrain are essential for new learning of both object and event-like memories in the monkey. Our model of learning in the primate brain rests on the proposal that there is a route of communication between the frontal cortex and inferior temporal cortex and hippocampus via the basal forebrain, which is critical for memory encoding. Interruption to this circuit at any stage will result in a severe and global anterograde amnesia." @default.
- W2057930062 created "2016-06-24" @default.
- W2057930062 creator A5039856437 @default.
- W2057930062 creator A5068843753 @default.
- W2057930062 date "2003-01-01" @default.
- W2057930062 modified "2023-10-16" @default.
- W2057930062 title "A Cholinergic Explanation of Dense Amnesia" @default.
- W2057930062 cites W1503177707 @default.
- W2057930062 cites W1515038794 @default.
- W2057930062 cites W1516658808 @default.
- W2057930062 cites W1572323180 @default.
- W2057930062 cites W1598800837 @default.
- W2057930062 cites W1605797652 @default.
- W2057930062 cites W1730980508 @default.
- W2057930062 cites W1766797326 @default.
- W2057930062 cites W1840705577 @default.
- W2057930062 cites W1897489955 @default.
- W2057930062 cites W1968256939 @default.
- W2057930062 cites W1970079995 @default.
- W2057930062 cites W1971392964 @default.
- W2057930062 cites W1971715733 @default.
- W2057930062 cites W1972759599 @default.
- W2057930062 cites W1979132989 @default.
- W2057930062 cites W1980310396 @default.
- W2057930062 cites W1987473188 @default.
- W2057930062 cites W1987709708 @default.
- W2057930062 cites W1989028533 @default.
- W2057930062 cites W1990532346 @default.
- W2057930062 cites W1990697121 @default.
- W2057930062 cites W1994343347 @default.
- W2057930062 cites W2006039762 @default.
- W2057930062 cites W2006340959 @default.
- W2057930062 cites W2009434646 @default.
- W2057930062 cites W2009619160 @default.
- W2057930062 cites W2013854477 @default.
- W2057930062 cites W2013877950 @default.
- W2057930062 cites W2014214802 @default.
- W2057930062 cites W2015011458 @default.
- W2057930062 cites W2019401192 @default.
- W2057930062 cites W2019710249 @default.
- W2057930062 cites W2021346798 @default.
- W2057930062 cites W2027073047 @default.
- W2057930062 cites W2028848902 @default.
- W2057930062 cites W2030193511 @default.
- W2057930062 cites W2033323701 @default.
- W2057930062 cites W2033773135 @default.
- W2057930062 cites W2036857168 @default.
- W2057930062 cites W2037338304 @default.
- W2057930062 cites W2037978784 @default.
- W2057930062 cites W2039276784 @default.
- W2057930062 cites W2041374893 @default.
- W2057930062 cites W2045359772 @default.
- W2057930062 cites W2051337399 @default.
- W2057930062 cites W2052515926 @default.
- W2057930062 cites W2054577109 @default.
- W2057930062 cites W2055508178 @default.
- W2057930062 cites W2062706679 @default.
- W2057930062 cites W2063582503 @default.
- W2057930062 cites W2064864838 @default.
- W2057930062 cites W2066218556 @default.
- W2057930062 cites W2073892790 @default.
- W2057930062 cites W2079753258 @default.
- W2057930062 cites W2080575216 @default.
- W2057930062 cites W2082501635 @default.
- W2057930062 cites W2083032624 @default.
- W2057930062 cites W2083818519 @default.
- W2057930062 cites W2084760654 @default.
- W2057930062 cites W2087298647 @default.
- W2057930062 cites W2087659744 @default.
- W2057930062 cites W2092082847 @default.
- W2057930062 cites W2093374391 @default.
- W2057930062 cites W2093377483 @default.
- W2057930062 cites W2095329714 @default.
- W2057930062 cites W2099102233 @default.
- W2057930062 cites W2099630522 @default.
- W2057930062 cites W2103692957 @default.
- W2057930062 cites W2108503207 @default.
- W2057930062 cites W2109635955 @default.
- W2057930062 cites W2111767975 @default.
- W2057930062 cites W2112650290 @default.
- W2057930062 cites W2112964034 @default.
- W2057930062 cites W2114700221 @default.
- W2057930062 cites W2115990514 @default.
- W2057930062 cites W2133052659 @default.
- W2057930062 cites W2133459825 @default.
- W2057930062 cites W2137022539 @default.
- W2057930062 cites W2137599726 @default.
- W2057930062 cites W2140405850 @default.
- W2057930062 cites W2154289885 @default.
- W2057930062 cites W2154521931 @default.
- W2057930062 cites W2157666661 @default.
- W2057930062 cites W2159404024 @default.
- W2057930062 cites W2160663597 @default.
- W2057930062 cites W2161082374 @default.
- W2057930062 cites W2165651695 @default.
- W2057930062 cites W2166272307 @default.
- W2057930062 cites W2166863203 @default.
- W2057930062 cites W2170156826 @default.