FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2057973334> ?p ?o ?g. }

• W2057973334 abstract "Aim: We have undertaken an attempt to compare the application efficacy of the proliferative activity markers in the differential diagnosis of thyroid Hurthle cell tumors using the PCNA and Ki-67 labeling and AgNOR visualization techniques. Materials and methods: The present work is a retrospective analysis of proliferative potential in 40 Hurthle cell tumors, on paraffin blocks: 10 Hurthle cell carcinomas (HCC), 16 Hurthle cell adenomas (HCA) and 14 hyperplastic nodules with Hurthle cell metaplasia (HCM). The evaluation of the mean number of nucleolar organizer regions (NORs) per nucleus and the proliferative index (PI-the percentage of PCNA and Ki-67 positive cells) was performed using staining silver impregnation method and antibodies against PCNA (clone PC 10) and Ki-67 (clone MIB-1) in LSAB detection Kit and visualization with DAB (diaminobenzidine). U-Mann-Whitney test was used for statistical analysis. The difference was considered significant for p<0.05. Results: The values of PI-PCNA, PI-Ki-67 as well as the mean AgNOR counts in nuclei were: 25.5, 12.8, and 5.0 in HCC; 7.6, 4.9, and 3.1 in HCA and respectively 5.1, 4.0 and 2.3 in HCM. Statistically significant differences were found in all the proliferative activity markers between malignant and benign tumors: HCM: HCC (p<0.0001) and HCC: HCA (p<0.001). Indifferently of the examined markers and the method of quantification of the reaction, we did not found significant differences between hyperplastic nodules with Hurthle cell metaplasia and oncocytic adenomas (p< 0.07). Conclusions: PI-PCNA, PI Ki-67 and mean AgNOR/ nucleus, used as markers for the appreciation of proliferative activity of oncocytic thyroid tumors (classified as adenomas, carcinomas and hyperplastic nodules with Hurthle cells), reflect differences between the studied thyroid lesions. Our results indicate the utility of these parameters in the differentiation of the benign oncocytic tumors from the malignant ones." @default.
• W2057973334 created "2016-06-24" @default.
• W2057973334 creator A5020299965 @default.
• W2057973334 date "2006-01-01" @default.
• W2057973334 modified "2023-09-25" @default.
• W2057973334 title "Proliferative Activity of Thyroid Hurthle Cell Tumors" @default.
• W2057973334 cites W1270433070 @default.
• W2057973334 cites W134095429 @default.
• W2057973334 cites W1553432789 @default.
• W2057973334 cites W1926181167 @default.
• W2057973334 cites W1944130357 @default.
• W2057973334 cites W1957619393 @default.
• W2057973334 cites W1966325191 @default.
• W2057973334 cites W1975640639 @default.
• W2057973334 cites W1978676534 @default.
• W2057973334 cites W1980801718 @default.
• W2057973334 cites W1985139281 @default.
• W2057973334 cites W1990067943 @default.
• W2057973334 cites W1992456677 @default.
• W2057973334 cites W1993687544 @default.
• W2057973334 cites W2001061126 @default.
• W2057973334 cites W2013480174 @default.
• W2057973334 cites W2024679740 @default.
• W2057973334 cites W2026415923 @default.
• W2057973334 cites W2027291327 @default.
• W2057973334 cites W2028863958 @default.
• W2057973334 cites W2036227533 @default.
• W2057973334 cites W2037831471 @default.
• W2057973334 cites W2039685885 @default.
• W2057973334 cites W2043221676 @default.
• W2057973334 cites W2043571099 @default.
• W2057973334 cites W2046599355 @default.
• W2057973334 cites W2047217299 @default.
• W2057973334 cites W2071532626 @default.
• W2057973334 cites W2080152381 @default.
• W2057973334 cites W2080981370 @default.
• W2057973334 cites W2081028340 @default.
• W2057973334 cites W2097503890 @default.
• W2057973334 cites W2102786229 @default.
• W2057973334 cites W2146146910 @default.
• W2057973334 cites W2162942802 @default.
• W2057973334 cites W2182502432 @default.
• W2057973334 cites W2318795923 @default.
• W2057973334 cites W2405861847 @default.
• W2057973334 cites W2464389119 @default.
• W2057973334 cites W274027041 @default.
• W2057973334 cites W2915860898 @default.
• W2057973334 cites W318818838 @default.
• W2057973334 cites W628626057 @default.
• W2057973334 cites W2313064275 @default.
• W2057973334 doi "https://doi.org/10.4183/aeb.2006.269" @default.
• W2057973334 hasPublicationYear "2006" @default.
• W2057973334 type Work @default.
• W2057973334 sameAs 2057973334 @default.
• W2057973334 citedByCount "1" @default.
• W2057973334 countsByYear W20579733342012 @default.
• W2057973334 crossrefType "journal-article" @default.
• W2057973334 hasAuthorship W2057973334A5020299965 @default.
• W2057973334 hasConcept C118552586 @default.
• W2057973334 hasConcept C126322002 @default.
• W2057973334 hasConcept C142724271 @default.
• W2057973334 hasConcept C1491633281 @default.
• W2057973334 hasConcept C183873130 @default.
• W2057973334 hasConcept C184604658 @default.
• W2057973334 hasConcept C185592680 @default.
• W2057973334 hasConcept C204232928 @default.
• W2057973334 hasConcept C2777428134 @default.
• W2057973334 hasConcept C2777562237 @default.
• W2057973334 hasConcept C2777751288 @default.
• W2057973334 hasConcept C2779022025 @default.
• W2057973334 hasConcept C2780674462 @default.
• W2057973334 hasConcept C2780723820 @default.
• W2057973334 hasConcept C2908820407 @default.
• W2057973334 hasConcept C34688535 @default.
• W2057973334 hasConcept C526584372 @default.
• W2057973334 hasConcept C55493867 @default.
• W2057973334 hasConcept C71924100 @default.
• W2057973334 hasConceptScore W2057973334C118552586 @default.
• W2057973334 hasConceptScore W2057973334C126322002 @default.
• W2057973334 hasConceptScore W2057973334C142724271 @default.
• W2057973334 hasConceptScore W2057973334C1491633281 @default.
• W2057973334 hasConceptScore W2057973334C183873130 @default.
• W2057973334 hasConceptScore W2057973334C184604658 @default.
• W2057973334 hasConceptScore W2057973334C185592680 @default.
• W2057973334 hasConceptScore W2057973334C204232928 @default.
• W2057973334 hasConceptScore W2057973334C2777428134 @default.
• W2057973334 hasConceptScore W2057973334C2777562237 @default.
• W2057973334 hasConceptScore W2057973334C2777751288 @default.
• W2057973334 hasConceptScore W2057973334C2779022025 @default.
• W2057973334 hasConceptScore W2057973334C2780674462 @default.
• W2057973334 hasConceptScore W2057973334C2780723820 @default.
• W2057973334 hasConceptScore W2057973334C2908820407 @default.
• W2057973334 hasConceptScore W2057973334C34688535 @default.
• W2057973334 hasConceptScore W2057973334C526584372 @default.
• W2057973334 hasConceptScore W2057973334C55493867 @default.
• W2057973334 hasConceptScore W2057973334C71924100 @default.
• W2057973334 hasLocation W20579733341 @default.
• W2057973334 hasOpenAccess W2057973334 @default.
• W2057973334 hasPrimaryLocation W20579733341 @default.
• W2057973334 hasRelatedWork W2182502432 @default.

• next