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- W2057982308 abstract "1. The depolarization induced by substance P (2 × 10−8 mol) on the ventral root of the isolated frog spinal cord was not affected by baclofen (10−4 M) in the normal medium, whereas the depolarization in the tetrodotoxin-treated or Ca2+-free, 1.8 mM Mg2+ medium-perfused preparation was significantly reduced by baclofen. 2. The depolarization induced by l-glutamate (2 × 10−7 mol) was not affected by baclofen in normal and also in TTX- or Ca2+-free, 1.8 mM Mg2+-treated preparation. 3. The results suggest that baclofen specifically antagonizes the depolarization induced by substance P at postsynaptic membrane." @default.
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- W2057982308 date "1981-01-01" @default.
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- W2057982308 title "Antagonistic action of baclofen on substance P-induced depolarization in the isolated spinal cord of the frog" @default.
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- W2057982308 doi "https://doi.org/10.1016/0306-3623(81)90004-5" @default.
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