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- W2057994906 endingPage "1953" @default.
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- W2057994906 abstract "T cell epitopes are peptides, for instance derived from foreign, mutated or overexpressed proteins, that are displayed by MHC molecules on the cell surface and that are recognized by T lymphocytes. Knowledge of the identity of epitopes displayed by MHC molecules is of high value for diagnostic purposes and for the development of prophylactic and therapeutic immunotherapy regimens. Here we review key techniques in MHC class I epitope definition and we discuss recent developments in epitope discovery and their implications. Developments in epitope discovery strategies should ultimately lead to the definition of the MHC-associated peptidome." @default.
- W2057994906 created "2016-06-24" @default.
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- W2057994906 date "2010-09-01" @default.
- W2057994906 modified "2023-10-14" @default.
- W2057994906 title "Technologies for MHC class I immunoproteomics" @default.
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- W2057994906 doi "https://doi.org/10.1016/j.jprot.2010.05.009" @default.
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