FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2058004066> ?p ?o ?g. }

• W2058004066 endingPage "39" @default.
• W2058004066 startingPage "25" @default.
• W2058004066 abstract "Completion of the fission yeast genome sequence has opened up possibilities for post-genomic approaches. We have constructed a DNA microarray for genome-wide gene expression analysis in fission yeast. The microarray contains DNA fragments, PCR-amplified from a genomic DNA template, that represent > 99% of the 5000 or so annotated fission yeast genes, as well as a number of control sequences. The GenomePRIDE software used attempts to design similarly sized DNA fragments corresponding to gene regions within single exons, near the 3′-end of genes that lack homology to other fission yeast genes. To validate the design and utility of the array, we studied expression changes after a 2 h temperature shift from 25 °C to 36 °C, conditions widely used when studying temperature-sensitive mutants. Obligingly, the vast majority of genes do not change more than two-fold, supporting the widely held view that temperature-shift experiments specifically reveal phenotypes associated with temperature-sensitive mutants. However, we did identify a small group of genes that showed a reproducible change in expression. Importantly, most of these corresponded to previously characterized heat-shock genes, whose expression has been reported to change after more extreme temperature shifts than those used here. We conclude that the DNA microarray represents a useful resource for fission yeast researchers as well as the broader yeast community, since it will facilitate comparison with the distantly related budding yeast, Saccharomyces cerevisiae. To maximize the utility of this resource, the array and its component parts are fully described in On-line Supplementary Information and are also available commercially. Copyright © 2003 John Wiley & Sons, Ltd." @default.
• W2058004066 created "2016-06-24" @default.
• W2058004066 creator A5001301955 @default.
• W2058004066 creator A5009628707 @default.
• W2058004066 creator A5019244899 @default.
• W2058004066 creator A5024116292 @default.
• W2058004066 creator A5035259297 @default.
• W2058004066 creator A5037818042 @default.
• W2058004066 creator A5053602175 @default.
• W2058004066 creator A5060444516 @default.
• W2058004066 creator A5062387652 @default.
• W2058004066 date "2004-01-15" @default.
• W2058004066 modified "2023-10-18" @default.
• W2058004066 title "A DNA microarray for fission yeast: minimal changes in global gene expression after temperature shift" @default.
• W2058004066 cites W1528221774 @default.
• W2058004066 cites W1550202981 @default.
• W2058004066 cites W1584704387 @default.
• W2058004066 cites W2017977879 @default.
• W2058004066 cites W2018237004 @default.
• W2058004066 cites W2023845765 @default.
• W2058004066 cites W2026406991 @default.
• W2058004066 cites W2027950141 @default.
• W2058004066 cites W2045718560 @default.
• W2058004066 cites W2096758922 @default.
• W2058004066 cites W2116402707 @default.
• W2058004066 cites W2117607208 @default.
• W2058004066 cites W2134809769 @default.
• W2058004066 cites W2141407136 @default.
• W2058004066 cites W2143941462 @default.
• W2058004066 cites W576020464 @default.
• W2058004066 doi "https://doi.org/10.1002/yea.1053" @default.
• W2058004066 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14745780" @default.
• W2058004066 hasPublicationYear "2004" @default.
• W2058004066 type Work @default.
• W2058004066 sameAs 2058004066 @default.
• W2058004066 citedByCount "40" @default.
• W2058004066 countsByYear W20580040662012 @default.
• W2058004066 countsByYear W20580040662013 @default.
• W2058004066 countsByYear W20580040662014 @default.
• W2058004066 countsByYear W20580040662015 @default.
• W2058004066 countsByYear W20580040662016 @default.
• W2058004066 countsByYear W20580040662020 @default.
• W2058004066 crossrefType "journal-article" @default.
• W2058004066 hasAuthorship W2058004066A5001301955 @default.
• W2058004066 hasAuthorship W2058004066A5009628707 @default.
• W2058004066 hasAuthorship W2058004066A5019244899 @default.
• W2058004066 hasAuthorship W2058004066A5024116292 @default.
• W2058004066 hasAuthorship W2058004066A5035259297 @default.
• W2058004066 hasAuthorship W2058004066A5037818042 @default.
• W2058004066 hasAuthorship W2058004066A5053602175 @default.
• W2058004066 hasAuthorship W2058004066A5060444516 @default.
• W2058004066 hasAuthorship W2058004066A5062387652 @default.
• W2058004066 hasConcept C104317684 @default.
• W2058004066 hasConcept C141231307 @default.
• W2058004066 hasConcept C143065580 @default.
• W2058004066 hasConcept C150194340 @default.
• W2058004066 hasConcept C17757408 @default.
• W2058004066 hasConcept C2777576037 @default.
• W2058004066 hasConcept C2779222958 @default.
• W2058004066 hasConcept C2779429346 @default.
• W2058004066 hasConcept C51679486 @default.
• W2058004066 hasConcept C54355233 @default.
• W2058004066 hasConcept C552990157 @default.
• W2058004066 hasConcept C70721500 @default.
• W2058004066 hasConcept C8415881 @default.
• W2058004066 hasConcept C86803240 @default.
• W2058004066 hasConcept C95371953 @default.
• W2058004066 hasConceptScore W2058004066C104317684 @default.
• W2058004066 hasConceptScore W2058004066C141231307 @default.
• W2058004066 hasConceptScore W2058004066C143065580 @default.
• W2058004066 hasConceptScore W2058004066C150194340 @default.
• W2058004066 hasConceptScore W2058004066C17757408 @default.
• W2058004066 hasConceptScore W2058004066C2777576037 @default.
• W2058004066 hasConceptScore W2058004066C2779222958 @default.
• W2058004066 hasConceptScore W2058004066C2779429346 @default.
• W2058004066 hasConceptScore W2058004066C51679486 @default.
• W2058004066 hasConceptScore W2058004066C54355233 @default.
• W2058004066 hasConceptScore W2058004066C552990157 @default.
• W2058004066 hasConceptScore W2058004066C70721500 @default.
• W2058004066 hasConceptScore W2058004066C8415881 @default.
• W2058004066 hasConceptScore W2058004066C86803240 @default.
• W2058004066 hasConceptScore W2058004066C95371953 @default.
• W2058004066 hasIssue "1" @default.
• W2058004066 hasLocation W20580040661 @default.
• W2058004066 hasLocation W20580040662 @default.
• W2058004066 hasOpenAccess W2058004066 @default.
• W2058004066 hasPrimaryLocation W20580040661 @default.
• W2058004066 hasRelatedWork W1483316219 @default.
• W2058004066 hasRelatedWork W170658859 @default.
• W2058004066 hasRelatedWork W1986892844 @default.
• W2058004066 hasRelatedWork W2034613288 @default.
• W2058004066 hasRelatedWork W2056932428 @default.
• W2058004066 hasRelatedWork W2412120523 @default.
• W2058004066 hasRelatedWork W2490137852 @default.
• W2058004066 hasRelatedWork W3023720143 @default.
• W2058004066 hasRelatedWork W3141198878 @default.
• W2058004066 hasRelatedWork W4310366902 @default.
• W2058004066 hasVolume "21" @default.

• next