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- W2058036367 abstract "Abstract The present study indicates that there is a combined action of alcohol and paraldehyde that may lead to death in some cases. Caution against overdosage should be exercised in their combined use. During the past several years, we have had the occasion to study nine cases in which the individual died suddenly and unexpectedly following paraldehyde therapy for acute alcoholism. Apparently these patients were in good health, other than for symptoms of alcolholism. Death occurred from 1 2 hour to 4 hours after administration of paraldehyde (30–60ml), and autopsy revealed no morphologic cause of death. Paraldehyde alone may produce death when the dose exceeds 120 ml, but the developing depression (coma) usually precedes death by at least 12 hours. Experiments with mice appear to confirm this combined action of alcohol and paraldehyde." @default.
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- W2058036367 date "1964-05-01" @default.
- W2058036367 modified "2023-09-26" @default.
- W2058036367 title "Study of death due to combined action of alcohol and paraldehyde in man" @default.
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- W2058036367 doi "https://doi.org/10.1016/0041-008x(64)90072-9" @default.
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