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• W2058091752 abstract "Standardized, robust and time-efficient localization of the human secondary somatosensory cortex (S2) is a challenge in clinical blood oxygen level dependent (BOLD) functional magnetic resonance imaging (fMRI). A fully automated tactile stimulation was optimized in seven right-handed volunteers at 1.5 T for minimum scan time, high BOLD signals and robust localization of S2 by systematically varying the applied block-design. All volunteers had six different fMRI measurements of five stimulation-baseline-cycles (sbc) each with equal block duration that was changed between the measurements from 6 s to 30 s. Additional data sets of 4, 3 and 2 cycles were generated post hoc resulting in a total of 168 data sets that were evaluated individually for BOLD-signal intensity (dS%), correlation to the hemodynamic reference function (r) and Euclidean coordinates (x, y, z). Using different block-designs the S2 activation was highly variable regarding the localization rate (lr), the hemispheric symmetry and the BOLD-signals. The protocol with 3 cycles, a block duration (dp) of 15 s and a total scan time (dt) of 105 s most robustly localized S2 (contralateral: lr = 71.4%, r = 0.65, dS = 1.01%; ipsilateral: lr = 100%, r = 0.6, dS = 1.14%) whereas the most time-efficient protocol to localize SI (sbc = 5, dp = 6 s, dt = 66 s) provided no robust localization of S2. Compared to other published fMRI protocols a scan time reduction up to 86% was achieved." @default.
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• W2058091752 date "2005-06-01" @default.
• W2058091752 modified "2023-10-17" @default.
• W2058091752 title "Time-efficient localization of the human secondary somatosensory cortex by functional magnetic resonance imaging" @default.
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• W2058091752 doi "https://doi.org/10.1016/j.neulet.2005.02.004" @default.
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