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- W2058092020 abstract "Peripheral nerve injury is a relatively commonly occurring trauma which seriously compromises the quality of life for many individuals. There is a major need to devise new treatment strategies, and one possible approach is to develop cellular therapies to bioengineer new nerve tissue and/or modulate the endogenous regenerative mechanisms within the peripheral nervous system. In this short review we describe how stem cells isolated from adipose tissue could be a suitable element of this approach. We describe the possible mechanisms through which the stem cells might exert a positive influence on peripheral nerve regeneration. These include their ability to differentiate into cells resembling Schwann cells and their secretion of a plethora of neurotrophic growth factors. We also review the literature describing the effects of these cells when tested using in vivo peripheral nerve injury models." @default.
- W2058092020 created "2016-06-24" @default.
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- W2058092020 date "2014-01-01" @default.
- W2058092020 modified "2023-10-18" @default.
- W2058092020 title "Adipose-Derived Stem Cells for Nerve Repair: Hype or Reality?" @default.
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- W2058092020 doi "https://doi.org/10.1159/000369336" @default.
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