FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2058095634> ?p ?o ?g. }

• W2058095634 endingPage "1101" @default.
• W2058095634 startingPage "1097" @default.
• W2058095634 abstract "Background: We have previously described both modification of allergen immunotherapy using peptide fragments, and reduced regulation of allergen stimulated T cells by CD4 + CD25 + T cells from allergic donors when compared with nonallergic controls. It has been suggested that allergen immunotherapy induces regulatory T cell activity: we hypothesized that allergen peptide immunotherapy might increase suppressive activity of CD4 + CD25 + T cells. Objective: To examine cat allergen‐stimulated CD4 T cell responses and their suppression by CD4 + CD25 + T cells before and after cat allergen peptide immunotherapy in a double‐blind placebo‐controlled study. Methods: Peripheral blood was obtained and stored before and after peptide immunotherapy or placebo treatment. CD4 + and CD4 + CD25 + were then isolated by immunomagnetic beads and cultured with allergen in vitro . Results: Comparing cells from blood taken before with that after peptide immunotherapy there was a significant reduction in both proliferation and IL‐13 production by allergen‐stimulated CD4+ T cells, whereas no change was seen after placebo. CD4 + CD25 + T cells suppressed both proliferation and IL‐13 production by CD4 + CD25 − T cells before and after therapy but peptide therapy was not associated with any change in suppressive activity of these cells. Conclusion: Allergen peptide immunotherapy alters T cell response to allergen through mechanisms other than changes in CD4 + CD25 + T cell suppression." @default.
• W2058095634 created "2016-06-24" @default.
• W2058095634 creator A5012458363 @default.
• W2058095634 creator A5051875070 @default.
• W2058095634 creator A5052782370 @default.
• W2058095634 creator A5064099470 @default.
• W2058095634 creator A5077280281 @default.
• W2058095634 date "2004-09-07" @default.
• W2058095634 modified "2023-10-16" @default.
• W2058095634 title "Cat allergen peptide immunotherapy reduces CD4+ T cell responses to cat allergen but does not alter suppression by CD4+ CD25+ T cells: a double-blind placebo-controlled study" @default.
• W2058095634 cites W1493122966 @default.
• W2058095634 cites W1526621387 @default.
• W2058095634 cites W1536322469 @default.
• W2058095634 cites W1611284225 @default.
• W2058095634 cites W1763723140 @default.
• W2058095634 cites W1972139541 @default.
• W2058095634 cites W1976640573 @default.
• W2058095634 cites W2002614529 @default.
• W2058095634 cites W2047456823 @default.
• W2058095634 cites W2048994961 @default.
• W2058095634 cites W2068471769 @default.
• W2058095634 cites W2093740248 @default.
• W2058095634 cites W2104852612 @default.
• W2058095634 cites W2122445377 @default.
• W2058095634 cites W2124566107 @default.
• W2058095634 cites W2125805192 @default.
• W2058095634 cites W2127755180 @default.
• W2058095634 cites W2130614990 @default.
• W2058095634 cites W2138989637 @default.
• W2058095634 cites W2142492100 @default.
• W2058095634 cites W2151677607 @default.
• W2058095634 cites W2152772601 @default.
• W2058095634 cites W2161074777 @default.
• W2058095634 cites W2166685437 @default.
• W2058095634 cites W2312829609 @default.
• W2058095634 cites W2564152524 @default.
• W2058095634 cites W4238104984 @default.
• W2058095634 cites W4313324526 @default.
• W2058095634 doi "https://doi.org/10.1111/j.1398-9995.2004.00601.x" @default.
• W2058095634 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15355469" @default.
• W2058095634 hasPublicationYear "2004" @default.
• W2058095634 type Work @default.
• W2058095634 sameAs 2058095634 @default.
• W2058095634 citedByCount "73" @default.
• W2058095634 countsByYear W20580956342012 @default.
• W2058095634 countsByYear W20580956342013 @default.
• W2058095634 countsByYear W20580956342014 @default.
• W2058095634 countsByYear W20580956342015 @default.
• W2058095634 countsByYear W20580956342016 @default.
• W2058095634 countsByYear W20580956342017 @default.
• W2058095634 countsByYear W20580956342018 @default.
• W2058095634 countsByYear W20580956342019 @default.
• W2058095634 countsByYear W20580956342021 @default.
• W2058095634 countsByYear W20580956342023 @default.
• W2058095634 crossrefType "journal-article" @default.
• W2058095634 hasAuthorship W2058095634A5012458363 @default.
• W2058095634 hasAuthorship W2058095634A5051875070 @default.
• W2058095634 hasAuthorship W2058095634A5052782370 @default.
• W2058095634 hasAuthorship W2058095634A5064099470 @default.
• W2058095634 hasAuthorship W2058095634A5077280281 @default.
• W2058095634 hasConcept C203014093 @default.
• W2058095634 hasConcept C207480886 @default.
• W2058095634 hasConcept C2776090121 @default.
• W2058095634 hasConcept C2777701055 @default.
• W2058095634 hasConcept C2779787640 @default.
• W2058095634 hasConcept C2780510475 @default.
• W2058095634 hasConcept C71924100 @default.
• W2058095634 hasConcept C79484868 @default.
• W2058095634 hasConcept C8891405 @default.
• W2058095634 hasConceptScore W2058095634C203014093 @default.
• W2058095634 hasConceptScore W2058095634C207480886 @default.
• W2058095634 hasConceptScore W2058095634C2776090121 @default.
• W2058095634 hasConceptScore W2058095634C2777701055 @default.
• W2058095634 hasConceptScore W2058095634C2779787640 @default.
• W2058095634 hasConceptScore W2058095634C2780510475 @default.
• W2058095634 hasConceptScore W2058095634C71924100 @default.
• W2058095634 hasConceptScore W2058095634C79484868 @default.
• W2058095634 hasConceptScore W2058095634C8891405 @default.
• W2058095634 hasIssue "10" @default.
• W2058095634 hasLocation W20580956341 @default.
• W2058095634 hasLocation W20580956342 @default.
• W2058095634 hasOpenAccess W2058095634 @default.
• W2058095634 hasPrimaryLocation W20580956341 @default.
• W2058095634 hasRelatedWork W2032428509 @default.
• W2058095634 hasRelatedWork W2094010564 @default.
• W2058095634 hasRelatedWork W2101014936 @default.
• W2058095634 hasRelatedWork W2116896714 @default.
• W2058095634 hasRelatedWork W2164797380 @default.
• W2058095634 hasRelatedWork W2235012284 @default.
• W2058095634 hasRelatedWork W2936367014 @default.
• W2058095634 hasRelatedWork W3000419270 @default.
• W2058095634 hasRelatedWork W3008758561 @default.
• W2058095634 hasRelatedWork W4232040028 @default.
• W2058095634 hasVolume "59" @default.
• W2058095634 isParatext "false" @default.
• W2058095634 isRetracted "false" @default.
• W2058095634 magId "2058095634" @default.
• W2058095634 workType "article" @default.