FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2058121574> ?p ?o ?g. }

• W2058121574 endingPage "397" @default.
• W2058121574 startingPage "389" @default.
• W2058121574 abstract "The aim of this analysis was to assess the early clinical results of pencil beam scanning proton therapy (PT) in the treatment of young children with non-metastatic atypical teratoid/rhabdoid tumor (ATRT) of the CNS. Fifteen children (male, n = 8, 53 %) were treated with PT between May 2008 and January 2013. Mean age at diagnosis was 17.4 ± 7.0 months. The localization was infratentorial in 9 (60 %) patients. Gross total resection of the primary tumors was achieved in 7 (47 %) patients. The dose administered focally under sedation was 54 Gy (RBE). After a median follow-up of 33.4 months (range 9.7–69.2), 3 (20 %), 4 (27 %) and 2 (13 %) patients presented with local failure (LF), distant brain failure (DBF) and spinal failure (SF), respectively. Six patients died, all of tumor progression. The 2-year overall- and progression-free survival was 64.6 and 66.0 %. Tumor location (supratentorial) and the extent of surgical resection (non-gross total resection) were negative prognostic factors for both OS and PFS. PT was well tolerated. No grade >2 acute toxicity was observed. The estimated 2-year toxicity-free survival was 90 %. As assessed by the PedsQoL proxy, no decrease in QoL was observed after PT. We conclude that PBS PT is an effective treatment for young children with ATRT. After PT, with or without concomitant chemotherapy, two third of the patients survived >2 years. Acute toxicity was manageable. Longer follow-up and larger numbers of patients are needed to assess long-term outcomes and treatment-induced toxicity." @default.
• W2058121574 created "2016-06-24" @default.
• W2058121574 creator A5010324476 @default.
• W2058121574 creator A5022660425 @default.
• W2058121574 creator A5026588801 @default.
• W2058121574 creator A5028670701 @default.
• W2058121574 creator A5035870007 @default.
• W2058121574 creator A5040876829 @default.
• W2058121574 creator A5042084730 @default.
• W2058121574 creator A5060976792 @default.
• W2058121574 creator A5064668846 @default.
• W2058121574 creator A5080102649 @default.
• W2058121574 creator A5090231642 @default.
• W2058121574 date "2014-11-02" @default.
• W2058121574 modified "2023-10-17" @default.
• W2058121574 title "Tumor control and QoL outcomes of very young children with atypical teratoid/rhabdoid Tumor treated with focal only chemo-radiation therapy using pencil beam scanning proton therapy" @default.
• W2058121574 cites W1486102782 @default.
• W2058121574 cites W1937850007 @default.
• W2058121574 cites W1979321534 @default.
• W2058121574 cites W1980879738 @default.
• W2058121574 cites W1991138928 @default.
• W2058121574 cites W2005730371 @default.
• W2058121574 cites W2011059767 @default.
• W2058121574 cites W2017872025 @default.
• W2058121574 cites W2020869516 @default.
• W2058121574 cites W2049584360 @default.
• W2058121574 cites W2058823951 @default.
• W2058121574 cites W2061684407 @default.
• W2058121574 cites W2066059189 @default.
• W2058121574 cites W2071710018 @default.
• W2058121574 cites W2074270331 @default.
• W2058121574 cites W2076222985 @default.
• W2058121574 cites W2078332269 @default.
• W2058121574 cites W2110029182 @default.
• W2058121574 cites W2132244178 @default.
• W2058121574 cites W2139571929 @default.
• W2058121574 cites W2151206030 @default.
• W2058121574 cites W2157517980 @default.
• W2058121574 cites W2163218852 @default.
• W2058121574 cites W4375905774 @default.
• W2058121574 cites W91815636 @default.
• W2058121574 doi "https://doi.org/10.1007/s11060-014-1648-2" @default.
• W2058121574 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25362544" @default.
• W2058121574 hasPublicationYear "2014" @default.
• W2058121574 type Work @default.
• W2058121574 sameAs 2058121574 @default.
• W2058121574 citedByCount "31" @default.
• W2058121574 countsByYear W20581215742015 @default.
• W2058121574 countsByYear W20581215742016 @default.
• W2058121574 countsByYear W20581215742017 @default.
• W2058121574 countsByYear W20581215742018 @default.
• W2058121574 countsByYear W20581215742019 @default.
• W2058121574 countsByYear W20581215742020 @default.
• W2058121574 countsByYear W20581215742021 @default.
• W2058121574 countsByYear W20581215742022 @default.
• W2058121574 crossrefType "journal-article" @default.
• W2058121574 hasAuthorship W2058121574A5010324476 @default.
• W2058121574 hasAuthorship W2058121574A5022660425 @default.
• W2058121574 hasAuthorship W2058121574A5026588801 @default.
• W2058121574 hasAuthorship W2058121574A5028670701 @default.
• W2058121574 hasAuthorship W2058121574A5035870007 @default.
• W2058121574 hasAuthorship W2058121574A5040876829 @default.
• W2058121574 hasAuthorship W2058121574A5042084730 @default.
• W2058121574 hasAuthorship W2058121574A5060976792 @default.
• W2058121574 hasAuthorship W2058121574A5064668846 @default.
• W2058121574 hasAuthorship W2058121574A5080102649 @default.
• W2058121574 hasAuthorship W2058121574A5090231642 @default.
• W2058121574 hasBestOaLocation W20581215742 @default.
• W2058121574 hasConcept C116263406 @default.
• W2058121574 hasConcept C126322002 @default.
• W2058121574 hasConcept C126838900 @default.
• W2058121574 hasConcept C141071460 @default.
• W2058121574 hasConcept C143998085 @default.
• W2058121574 hasConcept C2776694085 @default.
• W2058121574 hasConcept C2778467961 @default.
• W2058121574 hasConcept C2779384505 @default.
• W2058121574 hasConcept C29730261 @default.
• W2058121574 hasConcept C509974204 @default.
• W2058121574 hasConcept C529278444 @default.
• W2058121574 hasConcept C71924100 @default.
• W2058121574 hasConceptScore W2058121574C116263406 @default.
• W2058121574 hasConceptScore W2058121574C126322002 @default.
• W2058121574 hasConceptScore W2058121574C126838900 @default.
• W2058121574 hasConceptScore W2058121574C141071460 @default.
• W2058121574 hasConceptScore W2058121574C143998085 @default.
• W2058121574 hasConceptScore W2058121574C2776694085 @default.
• W2058121574 hasConceptScore W2058121574C2778467961 @default.
• W2058121574 hasConceptScore W2058121574C2779384505 @default.
• W2058121574 hasConceptScore W2058121574C29730261 @default.
• W2058121574 hasConceptScore W2058121574C509974204 @default.
• W2058121574 hasConceptScore W2058121574C529278444 @default.
• W2058121574 hasConceptScore W2058121574C71924100 @default.
• W2058121574 hasIssue "2" @default.
• W2058121574 hasLocation W20581215741 @default.
• W2058121574 hasLocation W20581215742 @default.
• W2058121574 hasLocation W20581215743 @default.
• W2058121574 hasLocation W20581215744 @default.
• W2058121574 hasLocation W20581215745 @default.

• next