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- W2058162103 abstract "Four protein fragments which span the entire hemagglutinin-neuraminidase protein (HN) of mumps virus were expressed in HeLa cells and cell extracts were tested for their capability to induce neutralizing antibodies in mice. Fragment HN3 (aa 213-372) was able to induce the production of hemagglutination-inhibiting and neutralizing antibodies. When a subfragment of HN3, the synthetic peptide NSTLGVKSAREF (aa 329-340 of HN) was used for immunization, hemagglutination-inhibiting and neutralizing antibodies against mumps wild type virus but not against the Urabe Am9 vaccine virus were raised. The peptide could, therefore, contain a new epitope, which may be critical for protective host humoral immune response." @default.
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- W2058162103 date "2001-04-01" @default.
- W2058162103 modified "2023-10-18" @default.
- W2058162103 title "Localization of a new neutralizing epitope on the mumps virus hemagglutinin–neuraminidase protein" @default.
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- W2058162103 doi "https://doi.org/10.1016/s0168-1702(00)00254-9" @default.
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