Matches in SemOpenAlex for { <https://semopenalex.org/work/W2058165392> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W2058165392 abstract "Ethyl (R)-2-hydroxy-4-phenylbutanoate ((R)-HPBE) was synthesized by asymmetric reduction of ethyl 2-oxo-4-phenylbutyrate with catalytic antibody NB5. Catalytic antibodies were generated by hybridoma technology. The hapten and holoantigen were synthesized. A lot of monoclonal antibodies were obtained. Catalytic antibody NB5 showed good reduction activity in synthesis of ethyl (R)-2-hydroxy-4-phenylbutanoate ((R)-HPBE). The biotransformation process was optimized with catalytic antibody NB5. The optimum reduction conditions were 30 0C, pH 6.0 and 210 min. NaBH4 in excess was added in reduction. Conversion was decreased with addition more amount of substrate. Conversion can reach 100% when initial substrate concentration was 30 umol/L. The enantiometric excess of ethyl (R)-2-hydroxy-4-phenylbutyrate was <99.9%." @default.
- W2058165392 created "2016-06-24" @default.
- W2058165392 creator A5033452791 @default.
- W2058165392 creator A5080129640 @default.
- W2058165392 date "2012-05-01" @default.
- W2058165392 modified "2023-09-22" @default.
- W2058165392 title "Asymmetric Synthesis of Ethyl (R)-2-hydroxy-4-phenylbutyrate with Catalytic Antibody NB5 as Catalyst" @default.
- W2058165392 cites W1505133393 @default.
- W2058165392 cites W1987604872 @default.
- W2058165392 cites W2019479638 @default.
- W2058165392 cites W2044865212 @default.
- W2058165392 cites W2047263972 @default.
- W2058165392 cites W2066937306 @default.
- W2058165392 cites W2077019915 @default.
- W2058165392 cites W2089692277 @default.
- W2058165392 cites W2951645612 @default.
- W2058165392 doi "https://doi.org/10.1109/icbeb.2012.85" @default.
- W2058165392 hasPublicationYear "2012" @default.
- W2058165392 type Work @default.
- W2058165392 sameAs 2058165392 @default.
- W2058165392 citedByCount "0" @default.
- W2058165392 crossrefType "proceedings-article" @default.
- W2058165392 hasAuthorship W2058165392A5033452791 @default.
- W2058165392 hasAuthorship W2058165392A5080129640 @default.
- W2058165392 hasConcept C134018914 @default.
- W2058165392 hasConcept C13965031 @default.
- W2058165392 hasConcept C146686406 @default.
- W2058165392 hasConcept C15752686 @default.
- W2058165392 hasConcept C161790260 @default.
- W2058165392 hasConcept C178790620 @default.
- W2058165392 hasConcept C181199279 @default.
- W2058165392 hasConcept C185592680 @default.
- W2058165392 hasConcept C18903297 @default.
- W2058165392 hasConcept C2777289219 @default.
- W2058165392 hasConcept C27881333 @default.
- W2058165392 hasConcept C2909310144 @default.
- W2058165392 hasConcept C86803240 @default.
- W2058165392 hasConceptScore W2058165392C134018914 @default.
- W2058165392 hasConceptScore W2058165392C13965031 @default.
- W2058165392 hasConceptScore W2058165392C146686406 @default.
- W2058165392 hasConceptScore W2058165392C15752686 @default.
- W2058165392 hasConceptScore W2058165392C161790260 @default.
- W2058165392 hasConceptScore W2058165392C178790620 @default.
- W2058165392 hasConceptScore W2058165392C181199279 @default.
- W2058165392 hasConceptScore W2058165392C185592680 @default.
- W2058165392 hasConceptScore W2058165392C18903297 @default.
- W2058165392 hasConceptScore W2058165392C2777289219 @default.
- W2058165392 hasConceptScore W2058165392C27881333 @default.
- W2058165392 hasConceptScore W2058165392C2909310144 @default.
- W2058165392 hasConceptScore W2058165392C86803240 @default.
- W2058165392 hasLocation W20581653921 @default.
- W2058165392 hasOpenAccess W2058165392 @default.
- W2058165392 hasPrimaryLocation W20581653921 @default.
- W2058165392 hasRelatedWork W1969535514 @default.
- W2058165392 hasRelatedWork W1980184505 @default.
- W2058165392 hasRelatedWork W1996286769 @default.
- W2058165392 hasRelatedWork W1996445147 @default.
- W2058165392 hasRelatedWork W2006575764 @default.
- W2058165392 hasRelatedWork W2021663095 @default.
- W2058165392 hasRelatedWork W2026383083 @default.
- W2058165392 hasRelatedWork W2037336652 @default.
- W2058165392 hasRelatedWork W2078458787 @default.
- W2058165392 hasRelatedWork W2083119689 @default.
- W2058165392 hasRelatedWork W2085652184 @default.
- W2058165392 hasRelatedWork W2131782734 @default.
- W2058165392 hasRelatedWork W2355064780 @default.
- W2058165392 hasRelatedWork W2358594727 @default.
- W2058165392 hasRelatedWork W2366586688 @default.
- W2058165392 hasRelatedWork W2373691854 @default.
- W2058165392 hasRelatedWork W2376705516 @default.
- W2058165392 hasRelatedWork W2386822737 @default.
- W2058165392 hasRelatedWork W2480962774 @default.
- W2058165392 hasRelatedWork W3007700780 @default.
- W2058165392 isParatext "false" @default.
- W2058165392 isRetracted "false" @default.
- W2058165392 magId "2058165392" @default.
- W2058165392 workType "article" @default.