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- W2058165516 abstract "Background: The lift capacity of a filler (ability to oppose deformation and flattening) relates to its suitability for correcting deeper wrinkles and folds, volumizing, and contouring. Lift capacity, considered as a function of both elastic modulus (G′) and gel cohesivity, can be expected to differ among products owing to proprietary manufacturing processes. Objectives: To compare the lift capabilities of 24-mg/ml smooth, cohesive gel fillers (with ∼6% and ∼8% crosslinking) and a 20-mg/ml granular consistency gel filler (∼2% crosslinking). Methods: G′ was measured using a parallel plate rheometer and the products were subjected to a small oscillatory strain. Cohesivity was measured using a linear compression test (quantitative) as well as a dye diffusion test (qualitative). Results: The 24-mg/ml smooth, cohesive gel filler had a lower G′ coupled with lower susceptibility to yield to a given strain versus the 20-mg/ml granular consistency gel filler. Both 24-mg/ml smooth, cohesive gel filler formulations demonstrated greater resistance to deformation in the linear compression test and lower rates of dye diffusion than the 20-mg/ml granular consistency gel filler. Conclusions: The 24-mg/ml smooth, cohesive HA gel fillers achieve a high lift capacity by combining higher cohesivity with lower relative G′ versus the 20-mg/ml granular consistency gel filler." @default.
- W2058165516 created "2016-06-24" @default.
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- W2058165516 date "2011-01-21" @default.
- W2058165516 modified "2023-10-01" @default.
- W2058165516 title "Lift capabilities of hyaluronic acid fillers" @default.
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- W2058165516 doi "https://doi.org/10.3109/14764172.2011.552609" @default.
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