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• W2058165769 abstract "Purpose: To study the relationship between roll-off (sudden increase in impedance) and spatial distribution of dehydrated tissue during RF ablation using a cooled electrode (temperatures around 100°C).Methods: We used a double approach: (1) theoretical modelling based on the finite element method, and (2) 20 ablations using an experimental study on ex vivo excised bovine liver in which we measured impedance progress and temperature at three points close to the electrode surface: 0.5 (T1), 1.5 (T2) and 2.5 (T3) mm from the tip. T2 was located exactly at the centre of the 30 mm long electrode.Results: Temperatures at T1 and T3 quickly rose to 100°C (at ≈20 and 40 s, respectively), while at the rise at T2 was somewhat slower, stabilized around 50 s and reached a maximum value of 99°C at about 60 s. Impedance reached a minimum of 65 Ω (plateau), began increasing at 50 s and continued rising throughout the procedure, reaching a value equal to the initial value at 70 s. Likewise, computed impedance dropped to ≈73 Ω (plateau), began increasing at 50 s and reached an impedance value equal to the initial value at ≈78 s, which approximately coincided with the time when the entire zone surrounding the electrode was within the 100°C isotherm.Conclusion: There is a close relationship between the moment at which roll-off occurs and the time when the entire electrode is completely encircled by the dehydrated tissue. The mid-electrode zone is the last in which tissue desiccation occurs." @default.
• W2058165769 created "2016-06-24" @default.
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• W2058165769 date "2012-01-11" @default.
• W2058165769 modified "2023-10-16" @default.
• W2058165769 title "Relationship between roll-off occurrence and spatial distribution of dehydrated tissue during RF ablation with cooled electrodes" @default.
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• W2058165769 doi "https://doi.org/10.3109/02656736.2011.631076" @default.
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