FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2058185449> ?p ?o ?g. }

• W2058185449 endingPage "303" @default.
• W2058185449 startingPage "299" @default.
• W2058185449 abstract "The medial septum and diagonal band of Broca (MSDB) are major afferents to the hippocampus and are important for learning, memory, and hippocampal theta rhythm. In the present study, we assessed the effect of cholinergic or noncholinergic MSDB lesions on the sequential learning of different goal locations in the same environment, a type of task that is proposed to require hippocampal theta rhythm. Rats were administered saline, 192-IgG saporin (SAP), or kainic acid (KA) into the MSDB and then behaviorally tested. On any day, a single arm of a radial maze was rewarded with food, but the location of this rewarded arm changed between days. As in previous studies, intraseptal SAP reduced the number of cholinergic neurons although sparing GABAergic septohippocampal neurons. KA had the reverse effect, reducing GABAergic septohippocampal neurons and sparing cholinergic neurons. KA, but not SAP, impaired performance on the repeated acquisition task. Saline and SAP rats showed rapid within-session learning, whereas KA rats were much slower to learn the goal location. Performance on a 30 min retention trial was also impaired, although this may be attributable to incomplete acquisition. These findings provide evidence that noncholinergic, but not cholinergic, MSDB neurons are important in helping the animal deal with high loads of memory interference, and provides partial support for the idea that hippocampal theta rhythm is involved." @default.
• W2058185449 created "2016-06-24" @default.
• W2058185449 creator A5012310778 @default.
• W2058185449 creator A5055947582 @default.
• W2058185449 creator A5072853922 @default.
• W2058185449 date "2007-01-10" @default.
• W2058185449 modified "2023-10-12" @default.
• W2058185449 title "Noncholinergic Lesions of the Medial Septum Impair Sequential Learning of Different Spatial Locations" @default.
• W2058185449 cites W1970616082 @default.
• W2058185449 cites W1974996330 @default.
• W2058185449 cites W1980415836 @default.
• W2058185449 cites W1982179824 @default.
• W2058185449 cites W1985927343 @default.
• W2058185449 cites W1993841935 @default.
• W2058185449 cites W1994067502 @default.
• W2058185449 cites W1994839334 @default.
• W2058185449 cites W1998241928 @default.
• W2058185449 cites W2003420020 @default.
• W2058185449 cites W2021280501 @default.
• W2058185449 cites W2028404719 @default.
• W2058185449 cites W2030193511 @default.
• W2058185449 cites W2044610087 @default.
• W2058185449 cites W2049948139 @default.
• W2058185449 cites W2053385545 @default.
• W2058185449 cites W2054262036 @default.
• W2058185449 cites W2058113871 @default.
• W2058185449 cites W2068180497 @default.
• W2058185449 cites W2068369739 @default.
• W2058185449 cites W2084338582 @default.
• W2058185449 cites W2085032350 @default.
• W2058185449 cites W2125181231 @default.
• W2058185449 cites W2133052659 @default.
• W2058185449 cites W2133153916 @default.
• W2058185449 cites W2162671157 @default.
• W2058185449 cites W2163909553 @default.
• W2058185449 cites W4240183934 @default.
• W2058185449 doi "https://doi.org/10.1523/jneurosci.4189-06.2007" @default.
• W2058185449 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3063940" @default.
• W2058185449 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17215389" @default.
• W2058185449 hasPublicationYear "2007" @default.
• W2058185449 type Work @default.
• W2058185449 sameAs 2058185449 @default.
• W2058185449 citedByCount "51" @default.
• W2058185449 countsByYear W20581854492012 @default.
• W2058185449 countsByYear W20581854492013 @default.
• W2058185449 countsByYear W20581854492014 @default.
• W2058185449 countsByYear W20581854492015 @default.
• W2058185449 countsByYear W20581854492016 @default.
• W2058185449 countsByYear W20581854492017 @default.
• W2058185449 countsByYear W20581854492018 @default.
• W2058185449 countsByYear W20581854492019 @default.
• W2058185449 countsByYear W20581854492020 @default.
• W2058185449 countsByYear W20581854492021 @default.
• W2058185449 countsByYear W20581854492022 @default.
• W2058185449 countsByYear W20581854492023 @default.
• W2058185449 crossrefType "journal-article" @default.
• W2058185449 hasAuthorship W2058185449A5012310778 @default.
• W2058185449 hasAuthorship W2058185449A5055947582 @default.
• W2058185449 hasAuthorship W2058185449A5072853922 @default.
• W2058185449 hasBestOaLocation W20581854491 @default.
• W2058185449 hasConcept C104966671 @default.
• W2058185449 hasConcept C115085202 @default.
• W2058185449 hasConcept C126322002 @default.
• W2058185449 hasConcept C148762608 @default.
• W2058185449 hasConcept C15744967 @default.
• W2058185449 hasConcept C159654299 @default.
• W2058185449 hasConcept C169760540 @default.
• W2058185449 hasConcept C170493617 @default.
• W2058185449 hasConcept C17077164 @default.
• W2058185449 hasConcept C203014093 @default.
• W2058185449 hasConcept C22885893 @default.
• W2058185449 hasConcept C2776108384 @default.
• W2058185449 hasConcept C2777705664 @default.
• W2058185449 hasConcept C2779177108 @default.
• W2058185449 hasConcept C2781161787 @default.
• W2058185449 hasConcept C2781260279 @default.
• W2058185449 hasConcept C542903549 @default.
• W2058185449 hasConcept C61174792 @default.
• W2058185449 hasConcept C71924100 @default.
• W2058185449 hasConceptScore W2058185449C104966671 @default.
• W2058185449 hasConceptScore W2058185449C115085202 @default.
• W2058185449 hasConceptScore W2058185449C126322002 @default.
• W2058185449 hasConceptScore W2058185449C148762608 @default.
• W2058185449 hasConceptScore W2058185449C15744967 @default.
• W2058185449 hasConceptScore W2058185449C159654299 @default.
• W2058185449 hasConceptScore W2058185449C169760540 @default.
• W2058185449 hasConceptScore W2058185449C170493617 @default.
• W2058185449 hasConceptScore W2058185449C17077164 @default.
• W2058185449 hasConceptScore W2058185449C203014093 @default.
• W2058185449 hasConceptScore W2058185449C22885893 @default.
• W2058185449 hasConceptScore W2058185449C2776108384 @default.
• W2058185449 hasConceptScore W2058185449C2777705664 @default.
• W2058185449 hasConceptScore W2058185449C2779177108 @default.
• W2058185449 hasConceptScore W2058185449C2781161787 @default.
• W2058185449 hasConceptScore W2058185449C2781260279 @default.
• W2058185449 hasConceptScore W2058185449C542903549 @default.
• W2058185449 hasConceptScore W2058185449C61174792 @default.
• W2058185449 hasConceptScore W2058185449C71924100 @default.

• next