FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2058189362> ?p ?o ?g. }

• W2058189362 endingPage "e74222" @default.
• W2058189362 startingPage "e74222" @default.
• W2058189362 abstract "LC3 is widely used marker for macroautophagy assays. After translation pro-LC3 is processed by Atg4 to expose C-terminal glycine residue for downstream conjugation reactions to accomplish the conversion of LC3-I to LC3-II. SDS-PAGE based Western blot (Wb) is generally utilized to quantify LC3-II levels where the LC3-I band migrates slower than LC3-II. We found that pro-human LC3B migrated at similar rate as LC3B-II in SDS-PAGE. The carboxyl-terminal five amino acids, particularly Lysine122 and Leucine123 of human LC3B play a major role in the faster migration of unprocessed LC3B, rendering it indistinguishable from LC3B-II in Wb assays. The unique faster migration of unprocessed LC3B than LC3B-I is also revealed in mouse LC3B, rat LC3B and rat LC3 but not in human LC3C. Our findings for the first time define pro-LC3 migration patterns for LC3 family member from human, mouse and rat species in SDS-PAGE. These findings provide a reference for pro-LC3 band patterns when Atg4 function is inhibited." @default.
• W2058189362 created "2016-06-24" @default.
• W2058189362 creator A5033407662 @default.
• W2058189362 creator A5046597133 @default.
• W2058189362 creator A5062076820 @default.
• W2058189362 creator A5063784705 @default.
• W2058189362 creator A5086603049 @default.
• W2058189362 date "2013-09-10" @default.
• W2058189362 modified "2023-10-17" @default.
• W2058189362 title "The Carboxyl-Terminal Amino Acids Render Pro-Human LC3B Migration Similar to Lipidated LC3B in SDS-PAGE" @default.
• W2058189362 cites W1496026049 @default.
• W2058189362 cites W1555054913 @default.
• W2058189362 cites W1964052965 @default.
• W2058189362 cites W1977767269 @default.
• W2058189362 cites W1988646463 @default.
• W2058189362 cites W1996144099 @default.
• W2058189362 cites W1998019811 @default.
• W2058189362 cites W2002563818 @default.
• W2058189362 cites W2003958562 @default.
• W2058189362 cites W2014205131 @default.
• W2058189362 cites W2063761428 @default.
• W2058189362 cites W2065575458 @default.
• W2058189362 cites W2065627978 @default.
• W2058189362 cites W2068153705 @default.
• W2058189362 cites W2068687154 @default.
• W2058189362 cites W2091417605 @default.
• W2058189362 cites W2093530916 @default.
• W2058189362 cites W2096246094 @default.
• W2058189362 cites W2111892050 @default.
• W2058189362 cites W2114806766 @default.
• W2058189362 cites W2128677681 @default.
• W2058189362 cites W2144714494 @default.
• W2058189362 cites W2146887271 @default.
• W2058189362 cites W2149771125 @default.
• W2058189362 cites W2164785771 @default.
• W2058189362 doi "https://doi.org/10.1371/journal.pone.0074222" @default.
• W2058189362 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3769297" @default.
• W2058189362 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24040206" @default.
• W2058189362 hasPublicationYear "2013" @default.
• W2058189362 type Work @default.
• W2058189362 sameAs 2058189362 @default.
• W2058189362 citedByCount "26" @default.
• W2058189362 countsByYear W20581893622015 @default.
• W2058189362 countsByYear W20581893622016 @default.
• W2058189362 countsByYear W20581893622018 @default.
• W2058189362 countsByYear W20581893622019 @default.
• W2058189362 countsByYear W20581893622020 @default.
• W2058189362 countsByYear W20581893622021 @default.
• W2058189362 countsByYear W20581893622022 @default.
• W2058189362 countsByYear W20581893622023 @default.
• W2058189362 crossrefType "journal-article" @default.
• W2058189362 hasAuthorship W2058189362A5033407662 @default.
• W2058189362 hasAuthorship W2058189362A5046597133 @default.
• W2058189362 hasAuthorship W2058189362A5062076820 @default.
• W2058189362 hasAuthorship W2058189362A5063784705 @default.
• W2058189362 hasAuthorship W2058189362A5086603049 @default.
• W2058189362 hasBestOaLocation W20581893621 @default.
• W2058189362 hasConcept C104317684 @default.
• W2058189362 hasConcept C121684516 @default.
• W2058189362 hasConcept C167625842 @default.
• W2058189362 hasConcept C185592680 @default.
• W2058189362 hasConcept C190283241 @default.
• W2058189362 hasConcept C203522944 @default.
• W2058189362 hasConcept C205711294 @default.
• W2058189362 hasConcept C2776415932 @default.
• W2058189362 hasConcept C2777756961 @default.
• W2058189362 hasConcept C2779664074 @default.
• W2058189362 hasConcept C3018824666 @default.
• W2058189362 hasConcept C41008148 @default.
• W2058189362 hasConcept C515207424 @default.
• W2058189362 hasConcept C55493867 @default.
• W2058189362 hasConcept C76155785 @default.
• W2058189362 hasConcept C86803240 @default.
• W2058189362 hasConcept C95444343 @default.
• W2058189362 hasConceptScore W2058189362C104317684 @default.
• W2058189362 hasConceptScore W2058189362C121684516 @default.
• W2058189362 hasConceptScore W2058189362C167625842 @default.
• W2058189362 hasConceptScore W2058189362C185592680 @default.
• W2058189362 hasConceptScore W2058189362C190283241 @default.
• W2058189362 hasConceptScore W2058189362C203522944 @default.
• W2058189362 hasConceptScore W2058189362C205711294 @default.
• W2058189362 hasConceptScore W2058189362C2776415932 @default.
• W2058189362 hasConceptScore W2058189362C2777756961 @default.
• W2058189362 hasConceptScore W2058189362C2779664074 @default.
• W2058189362 hasConceptScore W2058189362C3018824666 @default.
• W2058189362 hasConceptScore W2058189362C41008148 @default.
• W2058189362 hasConceptScore W2058189362C515207424 @default.
• W2058189362 hasConceptScore W2058189362C55493867 @default.
• W2058189362 hasConceptScore W2058189362C76155785 @default.
• W2058189362 hasConceptScore W2058189362C86803240 @default.
• W2058189362 hasConceptScore W2058189362C95444343 @default.
• W2058189362 hasIssue "9" @default.
• W2058189362 hasLocation W20581893621 @default.
• W2058189362 hasLocation W20581893622 @default.
• W2058189362 hasLocation W20581893623 @default.
• W2058189362 hasLocation W20581893624 @default.
• W2058189362 hasLocation W20581893625 @default.
• W2058189362 hasOpenAccess W2058189362 @default.

• next