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- W2058203482 abstract "Letters15 August 1993Lactic Acidosis and AIDSMilford FulopMilford FulopSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-119-4-199308150-00021 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Chattha and colleagues [1] recently described seven patients with the acquired immunodeficiency syndrome (AIDS) who had lactic acidosis without any obvious causes such as circulatory failure or bacteremia. Four patients died of cardiovascular collapse secondary to metabolic acidosis. The other patients left the hospital, but they too died of AIDS complications. Gopinath and coworkers [2] recently described a patient with AIDS whose lactic acidosis receded as his associated myopathy improved after withdrawal of zidovudine.Butterworth and colleagues [3] recently described thiamine deficiency in patients with AIDS, which has been proved to cause lactic acidosis in other kinds ...References1. Chattha G, Arieff AI, Cummings C, Tierney LM Jr. Lactic acidosis complicating the acquired immunodeficiency syndrome. Ann Intern Med. 1993; 118:37-9. Google Scholar2. Gopinath R, Hutcheon M, Cheemer-Dhadli S, Halperin M. Chronic lactic acidosis in a patient with acquired immunodeficiency syndrome and mitochondrial myopathy: biochemical studies. J Am Soc Nephrol. 1992; 3:1212-9. Google Scholar3. Butterworth RF, Gaudreau C, Vincelette J, Bourganlt A-M, Lamothe F, Nutini AM. Thiamine deficiency in AIDS. Lancet. 1991; 338:1086. Google Scholar4. Campbell CH. The severe lactic acidosis of thiamine deficiency. Acute pernicious or fulminating beri-beri. Lancet. 1984; 2:446-9. Google Scholar Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byLactic Acidosis Associated with Nucleoside Analog Therapy in an HIV-Positive PatientAcute pancreatitis with severe lactic acidosis in an HIV-infected patient on didanosine therapyTherapy of Lactic AcidosisThe Chemical Pathology of AIDS 15 August 1993Volume 119, Issue 4Page: 343-345KeywordsAIDSBrain diseasesDehydrogenasesEnzymesEthanolHeart failureLactatesLactic acidosisPyruvateThiamine ePublished: 15 August 2000 Issue Published: 15 August 1993 Copyright & PermissionsCopyright © 1993 by American College of Physicians. All Rights Reserved.PDF downloadLoading ..." @default.
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