Matches in SemOpenAlex for { <https://semopenalex.org/work/W2058230080> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W2058230080 endingPage "239" @default.
- W2058230080 startingPage "231" @default.
- W2058230080 abstract "The influence of hypoxemia on the brain content of several organic acids and NH+4, and its relationship to the accompanying hypocapnia was studied in unanesthetized rats subjected to hypoxemia for periods ranging between 2 hours and 7 days. Under acute conditions, ‘mild’ hypoxemia (FO2 = 9–10%) induced a rise in lactic acid and α-ketoglutaric acid. During ‘severe’ hypoxemia (FO2 = 6–7 %), these increases were greater and accompanied by increased γ-aminobutyric acid (GABA) and decreased glutamic and aspartic acid levels; glutamine and NH+4 remained normal. When hypocapnia was prevented, ‘severe’ hypoxemia induced only a rise in GABA and slight elevations in lactic and α-ketoglutaric acid. During prolonged severe hypoxemia, the effects on the brain amino acids were maintained throughout, indicating that they are independent from the intracerebral pH which should progressively normalize. The effect on lactic acid gradually disappeared. The results show that during hypocapnic hypoxemia the rise in brain GABA is hypoxemia dependent, the decrease in glutamic and aspartic acid is hypocapnia dependent and the increase in lactic acid is in a large way alkalosis dependent." @default.
- W2058230080 created "2016-06-24" @default.
- W2058230080 creator A5005428965 @default.
- W2058230080 creator A5023911576 @default.
- W2058230080 creator A5081889455 @default.
- W2058230080 date "1977-11-01" @default.
- W2058230080 modified "2023-09-25" @default.
- W2058230080 title "Brain amino acids in conscious rats in chronic normocapnic and hypocapnic hypoxemia" @default.
- W2058230080 cites W1592565027 @default.
- W2058230080 cites W1967305329 @default.
- W2058230080 cites W1970961139 @default.
- W2058230080 cites W1974409044 @default.
- W2058230080 cites W1995832822 @default.
- W2058230080 cites W1997745717 @default.
- W2058230080 cites W2007505650 @default.
- W2058230080 cites W2011782508 @default.
- W2058230080 cites W2022689287 @default.
- W2058230080 cites W2034399946 @default.
- W2058230080 cites W2036505219 @default.
- W2058230080 cites W2038862011 @default.
- W2058230080 cites W2073441246 @default.
- W2058230080 cites W2083554065 @default.
- W2058230080 cites W2110903518 @default.
- W2058230080 cites W2138052174 @default.
- W2058230080 cites W2145462399 @default.
- W2058230080 cites W2146250938 @default.
- W2058230080 cites W2283565530 @default.
- W2058230080 cites W2396594432 @default.
- W2058230080 cites W2415387928 @default.
- W2058230080 cites W2464945558 @default.
- W2058230080 doi "https://doi.org/10.1016/0034-5687(77)90105-0" @default.
- W2058230080 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/929000" @default.
- W2058230080 hasPublicationYear "1977" @default.
- W2058230080 type Work @default.
- W2058230080 sameAs 2058230080 @default.
- W2058230080 citedByCount "10" @default.
- W2058230080 crossrefType "journal-article" @default.
- W2058230080 hasAuthorship W2058230080A5005428965 @default.
- W2058230080 hasAuthorship W2058230080A5023911576 @default.
- W2058230080 hasAuthorship W2058230080A5081889455 @default.
- W2058230080 hasConcept C126322002 @default.
- W2058230080 hasConcept C134018914 @default.
- W2058230080 hasConcept C185592680 @default.
- W2058230080 hasConcept C2775920511 @default.
- W2058230080 hasConcept C2776779939 @default.
- W2058230080 hasConcept C2777037550 @default.
- W2058230080 hasConcept C2778740566 @default.
- W2058230080 hasConcept C2778866228 @default.
- W2058230080 hasConcept C2779349466 @default.
- W2058230080 hasConcept C42219234 @default.
- W2058230080 hasConcept C515207424 @default.
- W2058230080 hasConcept C523546767 @default.
- W2058230080 hasConcept C534529494 @default.
- W2058230080 hasConcept C54355233 @default.
- W2058230080 hasConcept C55493867 @default.
- W2058230080 hasConcept C71924100 @default.
- W2058230080 hasConcept C86803240 @default.
- W2058230080 hasConceptScore W2058230080C126322002 @default.
- W2058230080 hasConceptScore W2058230080C134018914 @default.
- W2058230080 hasConceptScore W2058230080C185592680 @default.
- W2058230080 hasConceptScore W2058230080C2775920511 @default.
- W2058230080 hasConceptScore W2058230080C2776779939 @default.
- W2058230080 hasConceptScore W2058230080C2777037550 @default.
- W2058230080 hasConceptScore W2058230080C2778740566 @default.
- W2058230080 hasConceptScore W2058230080C2778866228 @default.
- W2058230080 hasConceptScore W2058230080C2779349466 @default.
- W2058230080 hasConceptScore W2058230080C42219234 @default.
- W2058230080 hasConceptScore W2058230080C515207424 @default.
- W2058230080 hasConceptScore W2058230080C523546767 @default.
- W2058230080 hasConceptScore W2058230080C534529494 @default.
- W2058230080 hasConceptScore W2058230080C54355233 @default.
- W2058230080 hasConceptScore W2058230080C55493867 @default.
- W2058230080 hasConceptScore W2058230080C71924100 @default.
- W2058230080 hasConceptScore W2058230080C86803240 @default.
- W2058230080 hasIssue "2" @default.
- W2058230080 hasLocation W20582300801 @default.
- W2058230080 hasLocation W20582300802 @default.
- W2058230080 hasOpenAccess W2058230080 @default.
- W2058230080 hasPrimaryLocation W20582300801 @default.
- W2058230080 hasRelatedWork W1971690527 @default.
- W2058230080 hasRelatedWork W1972363332 @default.
- W2058230080 hasRelatedWork W1999568698 @default.
- W2058230080 hasRelatedWork W2002081391 @default.
- W2058230080 hasRelatedWork W2008692965 @default.
- W2058230080 hasRelatedWork W2023660858 @default.
- W2058230080 hasRelatedWork W2081940762 @default.
- W2058230080 hasRelatedWork W2112053897 @default.
- W2058230080 hasRelatedWork W2121738623 @default.
- W2058230080 hasRelatedWork W3342766 @default.
- W2058230080 hasVolume "31" @default.
- W2058230080 isParatext "false" @default.
- W2058230080 isRetracted "false" @default.
- W2058230080 magId "2058230080" @default.
- W2058230080 workType "article" @default.