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- W2058233719 abstract "Vaccination has the potential to eradicate mumps, and 82 countries now include a live attenuated mumps vaccine as part of their childhood vaccination programme. Although, monotypic, genetic variants of mumps virus (MuV) have been described based on comparison of the SH gene sequences, and at least seven genotypes have been identified. We now report the entire sequence of a recently isolated wild type MuV strain, Glouc1/UK96 (Glouc1) by direct sequencing of the cDNA obtained from cell culture fluid. The genome of this recent isolate was 15384 nucleotides in length. There were 579 nucleotide differences (3.8%) and 71 amino acid differences (1.5%) between Glouc1, a genotype G strain and Ur-AM9, a genotype B strain. Other MuV strains with available sequences were also compared with this pathological strain. The sequence of the contemporary strain reported here provides a picture of the variability of MuV over its entire genome (GenBank accession no. AF280799)." @default.
- W2058233719 created "2016-06-24" @default.
- W2058233719 creator A5012005202 @default.
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- W2058233719 creator A5081459152 @default.
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- W2058233719 date "2000-09-01" @default.
- W2058233719 modified "2023-09-27" @default.
- W2058233719 title "The genomic sequence of a contemporary wild-type mumps virus strain" @default.
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- W2058233719 doi "https://doi.org/10.1016/s0168-1702(00)00211-2" @default.
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