Matches in SemOpenAlex for { <https://semopenalex.org/work/W2058260090> ?p ?o ?g. }
- W2058260090 endingPage "610" @default.
- W2058260090 startingPage "604" @default.
- W2058260090 abstract "To investigate the clinical significance of tumor-infiltrating lymphocytes (TILs) within the tumor milieu, we quantitatively measured and compared the subpopulations of TILs in 24 patients with stage I–III breast carcinoma. Peripheral blood mononuclear cells (PBMCs), normal breast parenchyma-infiltrating lymphocytes (NILs), and TILs were isolated from tissue specimens and quantified by flow cytometry. The results showed that increased proportion of CD8+ T cells, with decreased proportion of CD4+ T cells, was significant in gated CD3+ TILs as compared to autologous NILs or PBMCs (P < 0.001). The tumor-infiltrating CD8+ T cells significantly increased with stage progression, reflected in a more strongly decreased CD4/CD8 percentage (P = 0.003). The CD4/CD8 percentage of TILs was strongly correlated with lymphovascular permeation and subsequent lymph node metastasis (P < 0.001). Increased percentages of tumor-infiltrating CD8+ T cells with decreased CD4/CD8 percentages are of prognostic importance for cancer progression in human breast cancer." @default.
- W2058260090 created "2016-06-24" @default.
- W2058260090 creator A5010941560 @default.
- W2058260090 creator A5023532447 @default.
- W2058260090 creator A5025862565 @default.
- W2058260090 creator A5026866724 @default.
- W2058260090 creator A5034080092 @default.
- W2058260090 creator A5045276882 @default.
- W2058260090 date "2008-12-01" @default.
- W2058260090 modified "2023-10-15" @default.
- W2058260090 title "Clinical significance of tumor-infiltrating lymphocytes in neoplastic progression and lymph node metastasis of human breast cancer" @default.
- W2058260090 cites W1123722611 @default.
- W2058260090 cites W1444462873 @default.
- W2058260090 cites W1480346895 @default.
- W2058260090 cites W1495708961 @default.
- W2058260090 cites W1546319410 @default.
- W2058260090 cites W1589348005 @default.
- W2058260090 cites W1598843567 @default.
- W2058260090 cites W1826114831 @default.
- W2058260090 cites W1878421783 @default.
- W2058260090 cites W1967404929 @default.
- W2058260090 cites W1973251492 @default.
- W2058260090 cites W1981919340 @default.
- W2058260090 cites W1984832220 @default.
- W2058260090 cites W1989927158 @default.
- W2058260090 cites W1992386229 @default.
- W2058260090 cites W2009433753 @default.
- W2058260090 cites W2013530786 @default.
- W2058260090 cites W2019994548 @default.
- W2058260090 cites W2025309264 @default.
- W2058260090 cites W2028036915 @default.
- W2058260090 cites W2033720551 @default.
- W2058260090 cites W2039891675 @default.
- W2058260090 cites W2045574978 @default.
- W2058260090 cites W2078742602 @default.
- W2058260090 cites W2079893379 @default.
- W2058260090 cites W2084059754 @default.
- W2058260090 cites W2084469135 @default.
- W2058260090 cites W2090177390 @default.
- W2058260090 cites W2115272863 @default.
- W2058260090 cites W2130794361 @default.
- W2058260090 cites W2134256683 @default.
- W2058260090 cites W2140905796 @default.
- W2058260090 cites W2156323704 @default.
- W2058260090 cites W2469707742 @default.
- W2058260090 doi "https://doi.org/10.1016/j.breast.2008.06.001" @default.
- W2058260090 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18656354" @default.
- W2058260090 hasPublicationYear "2008" @default.
- W2058260090 type Work @default.
- W2058260090 sameAs 2058260090 @default.
- W2058260090 citedByCount "47" @default.
- W2058260090 countsByYear W20582600902012 @default.
- W2058260090 countsByYear W20582600902013 @default.
- W2058260090 countsByYear W20582600902014 @default.
- W2058260090 countsByYear W20582600902015 @default.
- W2058260090 countsByYear W20582600902016 @default.
- W2058260090 countsByYear W20582600902019 @default.
- W2058260090 countsByYear W20582600902020 @default.
- W2058260090 countsByYear W20582600902021 @default.
- W2058260090 countsByYear W20582600902022 @default.
- W2058260090 countsByYear W20582600902023 @default.
- W2058260090 crossrefType "journal-article" @default.
- W2058260090 hasAuthorship W2058260090A5010941560 @default.
- W2058260090 hasAuthorship W2058260090A5023532447 @default.
- W2058260090 hasAuthorship W2058260090A5025862565 @default.
- W2058260090 hasAuthorship W2058260090A5026866724 @default.
- W2058260090 hasAuthorship W2058260090A5034080092 @default.
- W2058260090 hasAuthorship W2058260090A5045276882 @default.
- W2058260090 hasBestOaLocation W20582600901 @default.
- W2058260090 hasConcept C114684123 @default.
- W2058260090 hasConcept C121608353 @default.
- W2058260090 hasConcept C126322002 @default.
- W2058260090 hasConcept C137061746 @default.
- W2058260090 hasConcept C142724271 @default.
- W2058260090 hasConcept C146357865 @default.
- W2058260090 hasConcept C151730666 @default.
- W2058260090 hasConcept C167672396 @default.
- W2058260090 hasConcept C202751555 @default.
- W2058260090 hasConcept C203014093 @default.
- W2058260090 hasConcept C2778326572 @default.
- W2058260090 hasConcept C2778740770 @default.
- W2058260090 hasConcept C2779013556 @default.
- W2058260090 hasConcept C2779256057 @default.
- W2058260090 hasConcept C2780849966 @default.
- W2058260090 hasConcept C530470458 @default.
- W2058260090 hasConcept C553184892 @default.
- W2058260090 hasConcept C55493867 @default.
- W2058260090 hasConcept C71924100 @default.
- W2058260090 hasConcept C86803240 @default.
- W2058260090 hasConcept C8891405 @default.
- W2058260090 hasConceptScore W2058260090C114684123 @default.
- W2058260090 hasConceptScore W2058260090C121608353 @default.
- W2058260090 hasConceptScore W2058260090C126322002 @default.
- W2058260090 hasConceptScore W2058260090C137061746 @default.
- W2058260090 hasConceptScore W2058260090C142724271 @default.
- W2058260090 hasConceptScore W2058260090C146357865 @default.
- W2058260090 hasConceptScore W2058260090C151730666 @default.
- W2058260090 hasConceptScore W2058260090C167672396 @default.