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• W2058324077 abstract "Abstract Several characteristics of glycolic acid metabolism were measured in lactating and nonlactating goats by a primer dose plus 3-hour constant infusion technique. The average turnover rate of glycolic acid was 1.7g per hour, and no lactation effect was observed. The turnover time averaged 9.5 minutes with a half-life of 6.6 minutes. Administered 14 C-glycolic acid was rapidly oxidized to 14 CO 2 with 44% appearing in CO 2 by 5 hours. About 1% of total expired CO 2 was derived from glycolic acid. Some glycolic acid was incorporated into milk components. After 5 hours, .41% of the infused 14 C-glycolic acid was incorporated into casein, .08% into fat, and about 2% into lactose. During an identical period, 14 C-glucose was incorporated into casein, fat and lactose at .4%, .5% and 32% of the administered dose. Glycolic acid was detected also in rabbit, swine, and horse blood. Turnover rates of glycolic acid in a calf were similar to those in the goats, and after phlorizin treatment about the same amount of radioactivity was in urine glucose as was in milk lactose from the lactating goats. The rate of oxidation to CO 2 was somewhat slower. Only a trace of radioactive glycolic acid was excreted in the urine." @default.
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• W2058324077 date "1971-10-01" @default.
• W2058324077 modified "2023-09-29" @default.
• W2058324077 title "Metabolism of Glycolic Acid in Lactating and Nonlactating Goats and in a Calf" @default.
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• W2058324077 doi "https://doi.org/10.3168/jds.s0022-0302(71)86056-3" @default.
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