Matches in SemOpenAlex for { <https://semopenalex.org/work/W2058336218> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W2058336218 endingPage "602" @default.
- W2058336218 startingPage "602" @default.
- W2058336218 abstract "Fatty degeneration was frequently seen in patients with chronic massive rotator cuff (RC) tears. Surgical outcomes of the rotator cuff repair are deteriorated in cases with severe fatty muscle degeneration. Recently, Platelet rich plasma (PRP) was reported to suppress adipogenesis within the marrow. Furthermore, PRP can induce human tenocyte proliferation and collagen synthesis. Based on these backgrounds, we hypothesized that PRP could suppress adipogenesis of RC-derived cells. Human tissues were obtained from torn edges of human supraspinatus tendons during arthroscopic RC repair. For PRP preparation, 4 systemically healthy volunteers participated in this study, and PRP was prepared following the protocol of double spinning method. After cells were cultured in standard medium for 3 days, the cells were subjected to the following 2 kinds of treatment for 3 weeks, 1) adipogenic medium + 10% PRP (PRP group) and 2) adipogenic medium alone (Control group). Cell viability was measured by WST assay, and adipogenic differentiation was evaluated by real time PCR for adipogenic markers and Oil red-O staining. The cell viability in PRP group was significantly greater than the Control group. The real-time PCR revealed that the expressions of adipogenic markers was significantly suppressed in PRP group compared to the Control. Oil red-O staining showed that the number of positive cells in PRP group was significantly less than the Control. We firstly reported that PRP could suppress adipogenesis of RC-derived cells without inhibiting cell viability in vitro. Further animal studies will be needed to assess the in vivo effect of PRP on adipogenesis within RC." @default.
- W2058336218 created "2016-06-24" @default.
- W2058336218 creator A5000860759 @default.
- W2058336218 creator A5015195139 @default.
- W2058336218 creator A5017262688 @default.
- W2058336218 creator A5034762777 @default.
- W2058336218 creator A5042340996 @default.
- W2058336218 creator A5059385573 @default.
- W2058336218 creator A5064215891 @default.
- W2058336218 creator A5075628538 @default.
- W2058336218 date "2014-05-01" @default.
- W2058336218 modified "2023-10-16" @default.
- W2058336218 title "Inhibitory Effect of Platelet Rich Plasma on Adipogenesis of Rotator Cuff-Derived Cells" @default.
- W2058336218 doi "https://doi.org/10.1016/j.jse.2014.01.027" @default.
- W2058336218 hasPublicationYear "2014" @default.
- W2058336218 type Work @default.
- W2058336218 sameAs 2058336218 @default.
- W2058336218 citedByCount "0" @default.
- W2058336218 crossrefType "journal-article" @default.
- W2058336218 hasAuthorship W2058336218A5000860759 @default.
- W2058336218 hasAuthorship W2058336218A5015195139 @default.
- W2058336218 hasAuthorship W2058336218A5017262688 @default.
- W2058336218 hasAuthorship W2058336218A5034762777 @default.
- W2058336218 hasAuthorship W2058336218A5042340996 @default.
- W2058336218 hasAuthorship W2058336218A5059385573 @default.
- W2058336218 hasAuthorship W2058336218A5064215891 @default.
- W2058336218 hasAuthorship W2058336218A5075628538 @default.
- W2058336218 hasBestOaLocation W20583362181 @default.
- W2058336218 hasConcept C122927707 @default.
- W2058336218 hasConcept C126322002 @default.
- W2058336218 hasConcept C141071460 @default.
- W2058336218 hasConcept C142724271 @default.
- W2058336218 hasConcept C1491633281 @default.
- W2058336218 hasConcept C16685009 @default.
- W2058336218 hasConcept C185592680 @default.
- W2058336218 hasConcept C198826908 @default.
- W2058336218 hasConcept C202751555 @default.
- W2058336218 hasConcept C2776511800 @default.
- W2058336218 hasConcept C2780076745 @default.
- W2058336218 hasConcept C2780806160 @default.
- W2058336218 hasConcept C53227056 @default.
- W2058336218 hasConcept C55493867 @default.
- W2058336218 hasConcept C71924100 @default.
- W2058336218 hasConcept C74864618 @default.
- W2058336218 hasConcept C89560881 @default.
- W2058336218 hasConceptScore W2058336218C122927707 @default.
- W2058336218 hasConceptScore W2058336218C126322002 @default.
- W2058336218 hasConceptScore W2058336218C141071460 @default.
- W2058336218 hasConceptScore W2058336218C142724271 @default.
- W2058336218 hasConceptScore W2058336218C1491633281 @default.
- W2058336218 hasConceptScore W2058336218C16685009 @default.
- W2058336218 hasConceptScore W2058336218C185592680 @default.
- W2058336218 hasConceptScore W2058336218C198826908 @default.
- W2058336218 hasConceptScore W2058336218C202751555 @default.
- W2058336218 hasConceptScore W2058336218C2776511800 @default.
- W2058336218 hasConceptScore W2058336218C2780076745 @default.
- W2058336218 hasConceptScore W2058336218C2780806160 @default.
- W2058336218 hasConceptScore W2058336218C53227056 @default.
- W2058336218 hasConceptScore W2058336218C55493867 @default.
- W2058336218 hasConceptScore W2058336218C71924100 @default.
- W2058336218 hasConceptScore W2058336218C74864618 @default.
- W2058336218 hasConceptScore W2058336218C89560881 @default.
- W2058336218 hasIssue "5" @default.
- W2058336218 hasLocation W20583362181 @default.
- W2058336218 hasOpenAccess W2058336218 @default.
- W2058336218 hasPrimaryLocation W20583362181 @default.
- W2058336218 hasRelatedWork W1508724800 @default.
- W2058336218 hasRelatedWork W2197819866 @default.
- W2058336218 hasRelatedWork W2350152010 @default.
- W2058336218 hasRelatedWork W2357075379 @default.
- W2058336218 hasRelatedWork W2390281688 @default.
- W2058336218 hasRelatedWork W2400024650 @default.
- W2058336218 hasRelatedWork W2563288228 @default.
- W2058336218 hasRelatedWork W2621834629 @default.
- W2058336218 hasRelatedWork W2997251303 @default.
- W2058336218 hasRelatedWork W3210080395 @default.
- W2058336218 hasVolume "23" @default.
- W2058336218 isParatext "false" @default.
- W2058336218 isRetracted "false" @default.
- W2058336218 magId "2058336218" @default.
- W2058336218 workType "article" @default.