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- W2058366893 abstract "A measured number of cpm of radioiodine labeled thyroxine (131I-T4) in agar (2 or 4%) were implanted in the region of the paraventricular nuclei of the hypothalami of 33 rats. The rats were sacrificed 0.5, 2, 6 or 24 hr later and the number of cpm measured in the hypothalamus, the rest of the brain, liver, kidneys, thyroid and plasma. Cpm in hypothalamus and brain fell steadily over the 24 hr. By 0.5 hr 52% of cpm remained in the hypothalamus, by 2 hr 31 % remained, by 6 hr 15–20 % remained, and by 24 hr <1% remained at the site of implantation. The % cpm originally implanted which was found in liver rose to 7% at 6 hr, at which time 1 % of the implanted counts were present in each ml of plasma and 0.45% of the original cpm were present in the kidneys." @default.
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- W2058366893 date "1970-07-01" @default.
- W2058366893 modified "2023-09-27" @default.
- W2058366893 title "Disappearance of131I-Labeled Thyroxine (131I-T4) from Agar Pellets Implanted in the Hypothalamus of Rats" @default.
- W2058366893 doi "https://doi.org/10.1210/endo-87-1-176" @default.
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