Matches in SemOpenAlex for { <https://semopenalex.org/work/W2058371138> ?p ?o ?g. }
- W2058371138 endingPage "253" @default.
- W2058371138 startingPage "246" @default.
- W2058371138 abstract "Porcine S100A12 is a member of the S100 proteins, family of small acidic calcium-binding proteins characterized by the presence of two EF-hand motifs. These proteins are involved in many cellular events such as the regulation of protein phosphorylation, enzymatic activity, protein-protein interaction, Ca2+ homeostasis, inflammatory processes and intermediate filament polymerization. In addition, members of this family bind Zn2+ or Ca2+ with cooperative effect on binding. In this study, the gene sequence encoding porcine S100A12 was obtained by the synthetic gene approach using E. coli codon bias. Additionally, we report a thermodynamic study of the recombinant S100A12 using circular dichroism, fluorescence and isothermal titration calorimetry. The results of urea and temperature induced unfolding and refolding processes indicated a reversible two-state process. Also, the ANS fluorescence studies showed that in presence of divalent ions the protein exposes hydrophobic sites which could facilitate the interaction with other proteins and trigger the physiological responses." @default.
- W2058371138 created "2016-06-24" @default.
- W2058371138 creator A5003299263 @default.
- W2058371138 creator A5033752129 @default.
- W2058371138 creator A5039152855 @default.
- W2058371138 creator A5077242384 @default.
- W2058371138 date "2008-05-01" @default.
- W2058371138 modified "2023-10-18" @default.
- W2058371138 title "Structural stability and reversible unfolding of recombinant porcine S100A12" @default.
- W2058371138 cites W1420081820 @default.
- W2058371138 cites W1517690457 @default.
- W2058371138 cites W1530659187 @default.
- W2058371138 cites W1571243084 @default.
- W2058371138 cites W1581563868 @default.
- W2058371138 cites W1589237240 @default.
- W2058371138 cites W1971770269 @default.
- W2058371138 cites W1977214811 @default.
- W2058371138 cites W1982218724 @default.
- W2058371138 cites W1989644658 @default.
- W2058371138 cites W1998813486 @default.
- W2058371138 cites W1998826717 @default.
- W2058371138 cites W2002831204 @default.
- W2058371138 cites W2004328042 @default.
- W2058371138 cites W2005986251 @default.
- W2058371138 cites W2027351968 @default.
- W2058371138 cites W2033762592 @default.
- W2058371138 cites W2037753526 @default.
- W2058371138 cites W2050341653 @default.
- W2058371138 cites W2070792168 @default.
- W2058371138 cites W2071675524 @default.
- W2058371138 cites W2071736708 @default.
- W2058371138 cites W2100760178 @default.
- W2058371138 cites W2100837269 @default.
- W2058371138 cites W2123404680 @default.
- W2058371138 cites W2129771435 @default.
- W2058371138 cites W2138270253 @default.
- W2058371138 cites W2145538573 @default.
- W2058371138 cites W2146690077 @default.
- W2058371138 cites W2162739292 @default.
- W2058371138 cites W4240881582 @default.
- W2058371138 cites W4252589303 @default.
- W2058371138 doi "https://doi.org/10.1016/j.bpc.2008.02.013" @default.
- W2058371138 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18346834" @default.
- W2058371138 hasPublicationYear "2008" @default.
- W2058371138 type Work @default.
- W2058371138 sameAs 2058371138 @default.
- W2058371138 citedByCount "19" @default.
- W2058371138 countsByYear W20583711382013 @default.
- W2058371138 countsByYear W20583711382014 @default.
- W2058371138 countsByYear W20583711382015 @default.
- W2058371138 countsByYear W20583711382016 @default.
- W2058371138 countsByYear W20583711382017 @default.
- W2058371138 countsByYear W20583711382018 @default.
- W2058371138 countsByYear W20583711382019 @default.
- W2058371138 countsByYear W20583711382020 @default.
- W2058371138 countsByYear W20583711382023 @default.
- W2058371138 crossrefType "journal-article" @default.
- W2058371138 hasAuthorship W2058371138A5003299263 @default.
- W2058371138 hasAuthorship W2058371138A5033752129 @default.
- W2058371138 hasAuthorship W2058371138A5039152855 @default.
- W2058371138 hasAuthorship W2058371138A5077242384 @default.
- W2058371138 hasConcept C104317684 @default.
- W2058371138 hasConcept C12554922 @default.
- W2058371138 hasConcept C133571119 @default.
- W2058371138 hasConcept C156911925 @default.
- W2058371138 hasConcept C167625842 @default.
- W2058371138 hasConcept C178790620 @default.
- W2058371138 hasConcept C185592680 @default.
- W2058371138 hasConcept C204328495 @default.
- W2058371138 hasConcept C40767141 @default.
- W2058371138 hasConcept C42086223 @default.
- W2058371138 hasConcept C55493867 @default.
- W2058371138 hasConcept C74884574 @default.
- W2058371138 hasConcept C86803240 @default.
- W2058371138 hasConceptScore W2058371138C104317684 @default.
- W2058371138 hasConceptScore W2058371138C12554922 @default.
- W2058371138 hasConceptScore W2058371138C133571119 @default.
- W2058371138 hasConceptScore W2058371138C156911925 @default.
- W2058371138 hasConceptScore W2058371138C167625842 @default.
- W2058371138 hasConceptScore W2058371138C178790620 @default.
- W2058371138 hasConceptScore W2058371138C185592680 @default.
- W2058371138 hasConceptScore W2058371138C204328495 @default.
- W2058371138 hasConceptScore W2058371138C40767141 @default.
- W2058371138 hasConceptScore W2058371138C42086223 @default.
- W2058371138 hasConceptScore W2058371138C55493867 @default.
- W2058371138 hasConceptScore W2058371138C74884574 @default.
- W2058371138 hasConceptScore W2058371138C86803240 @default.
- W2058371138 hasIssue "3" @default.
- W2058371138 hasLocation W20583711381 @default.
- W2058371138 hasLocation W20583711382 @default.
- W2058371138 hasOpenAccess W2058371138 @default.
- W2058371138 hasPrimaryLocation W20583711381 @default.
- W2058371138 hasRelatedWork W1930279317 @default.
- W2058371138 hasRelatedWork W2014205933 @default.
- W2058371138 hasRelatedWork W2023972194 @default.
- W2058371138 hasRelatedWork W2025865006 @default.
- W2058371138 hasRelatedWork W2083410376 @default.
- W2058371138 hasRelatedWork W2113367092 @default.