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- W2058398512 abstract "We report on the development of a highly sensitive and cost efficient analysis system based on surface plasmonresonance spectroscopy. The advantage of our system consists of optical components being integrated into the sensorelement. These enable the uncritical optical coupling and, therefore, a simplified handling of the sensor plates withoutadditional optical adjustment. Manufacture by hot embossing or injection molding allows for a low cost production ofdisposable sensor elements.Furthermore, up to 50 measurement spots are arranged in parallel on a sensor plate to simultaneously detect a multitudeof different substances. The range of analytes to be determined is only limited by the specific affinity of theimmobilized capture molecules on the sensor surface. Optimized protein capture molecules for use in medical diagnosischips have to be developed for this purpose. The label free detection principle simplifies the probe preparation and leadsto a cost reduction compared with common fluorescence techniques. The development of a sensor element containing anumber of parallel measurement spots sufficient for a medically significant screening of relevant parameters in bloodsamples or other body fluids as well as the reliable detection of characteristic virus proteins will be shown in this paper." @default.
- W2058398512 created "2016-06-24" @default.
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- W2058398512 date "2004-06-16" @default.
- W2058398512 modified "2023-09-23" @default.
- W2058398512 title "Parallel SPR diagnostic system" @default.
- W2058398512 doi "https://doi.org/10.1117/12.524420" @default.
- W2058398512 hasPublicationYear "2004" @default.
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