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• W2058404786 abstract "In the hippocampus of mice lacking the gene for serine racemase (SR), a d-serine synthesizing enzyme, in the CaMKIIα-expressing neurons, we observed a significant decrease in the extracellular concentration of d-serine, a coagonist for the N-methyl-d-aspartate type glutamate receptor (NMDAR), and NMDAR hypofunction as revealed by diminished extracellular taurine concentrations after an intra-hippocampal NMDA infusion when compared to the wild type controls. Therefore, the neuronal SR could regulate the extracellular d-serine signaling responsible for NMDAR activation in the hippocampus." @default.
• W2058404786 created "2016-06-24" @default.
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• W2058404786 date "2015-03-18" @default.
• W2058404786 modified "2023-09-26" @default.
• W2058404786 title "Neuronal serine racemase regulates extracellular d-serine levels in the adult mouse hippocampus" @default.
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• W2058404786 doi "https://doi.org/10.1007/s00702-015-1388-2" @default.
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