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• W2058424097 abstract "Cathepsin G (CatG) is an endopeptidase that is associated with the early immune response. The synthetic compound cathepsin G inhibitor I (CGI-I) was tested for its ability to inhibit the activity of CatG via a new surface plasmon resonance imaging assay. CGI-I was immobilized on the gold surface of an SPR sensor that was first modified with 1-octadecanethiol. A concentration of CGI-I equal to 4.0 μg·mL-1 and a pH of 8.0 were found to give the best results. The dynamic response of the sensor ranges from 0.25 to 1.5 ng·mL-1, and the detection limit is 0.12 ng·mL-1. The sensor was applied to detect CatG in human saliva and white blood cells." @default.
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• W2058424097 date "2011-03-02" @default.
• W2058424097 modified "2023-09-27" @default.
• W2058424097 title "Development of an SPR imaging biosensor for determination of cathepsin G in saliva and white blood cells" @default.
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• W2058424097 doi "https://doi.org/10.1007/s00604-011-0569-4" @default.
• W2058424097 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3092066" @default.
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