Matches in SemOpenAlex for { <https://semopenalex.org/work/W2058432012> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W2058432012 endingPage "865" @default.
- W2058432012 startingPage "862" @default.
- W2058432012 abstract "To examine the mechanism potentially contributing to therapeutic efficacy of azelastine in allergic rhinitis and asthma, we studied the effect of azelastine on stimulated histamine release from basophils prepared as a mixed leukocyte suspension from human blood. Azelastine was found to significantly inhibit anti-IgE-stimulated basophil histamine release. Time-course experiments indicated that the inhibitory effect of azelastine was immediate and that preincubation of basophils in azelastine was not necessary. In dose-response experiments with azelastine, 1 to 100 mumol/L, significant inhibition of histamine release was consistently observed in azelastine concentrations greater than or equal to 10 mumol/L. This inhibition was dose dependent (r = 0.96; p less than 0.001) with maximal mean inhibition of 91 +/- 8% at 100 mumol/L of azelastine." @default.
- W2058432012 created "2016-06-24" @default.
- W2058432012 creator A5039194154 @default.
- W2058432012 creator A5069959810 @default.
- W2058432012 date "1989-05-01" @default.
- W2058432012 modified "2023-09-27" @default.
- W2058432012 title "Azelastine inhibits IgE-mediated human basophil histamine release" @default.
- W2058432012 cites W1498112163 @default.
- W2058432012 cites W1992812687 @default.
- W2058432012 cites W2000186658 @default.
- W2058432012 cites W2010959833 @default.
- W2058432012 cites W2014830269 @default.
- W2058432012 cites W2023084634 @default.
- W2058432012 cites W2031766799 @default.
- W2058432012 cites W2044715008 @default.
- W2058432012 cites W2053312234 @default.
- W2058432012 cites W2065149751 @default.
- W2058432012 cites W2069834296 @default.
- W2058432012 cites W2081219562 @default.
- W2058432012 cites W2084578532 @default.
- W2058432012 cites W2190330961 @default.
- W2058432012 cites W2257840380 @default.
- W2058432012 cites W2394981798 @default.
- W2058432012 cites W2400173945 @default.
- W2058432012 cites W2411035132 @default.
- W2058432012 cites W2411705726 @default.
- W2058432012 cites W2418432131 @default.
- W2058432012 doi "https://doi.org/10.1016/0091-6749(89)90096-1" @default.
- W2058432012 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2469707" @default.
- W2058432012 hasPublicationYear "1989" @default.
- W2058432012 type Work @default.
- W2058432012 sameAs 2058432012 @default.
- W2058432012 citedByCount "42" @default.
- W2058432012 countsByYear W20584320122021 @default.
- W2058432012 crossrefType "journal-article" @default.
- W2058432012 hasAuthorship W2058432012A5039194154 @default.
- W2058432012 hasAuthorship W2058432012A5069959810 @default.
- W2058432012 hasConcept C1122143 @default.
- W2058432012 hasConcept C141105273 @default.
- W2058432012 hasConcept C159654299 @default.
- W2058432012 hasConcept C185592680 @default.
- W2058432012 hasConcept C202751555 @default.
- W2058432012 hasConcept C203014093 @default.
- W2058432012 hasConcept C2776711897 @default.
- W2058432012 hasConcept C2777456892 @default.
- W2058432012 hasConcept C2780113039 @default.
- W2058432012 hasConcept C55493867 @default.
- W2058432012 hasConcept C71924100 @default.
- W2058432012 hasConcept C98274493 @default.
- W2058432012 hasConceptScore W2058432012C1122143 @default.
- W2058432012 hasConceptScore W2058432012C141105273 @default.
- W2058432012 hasConceptScore W2058432012C159654299 @default.
- W2058432012 hasConceptScore W2058432012C185592680 @default.
- W2058432012 hasConceptScore W2058432012C202751555 @default.
- W2058432012 hasConceptScore W2058432012C203014093 @default.
- W2058432012 hasConceptScore W2058432012C2776711897 @default.
- W2058432012 hasConceptScore W2058432012C2777456892 @default.
- W2058432012 hasConceptScore W2058432012C2780113039 @default.
- W2058432012 hasConceptScore W2058432012C55493867 @default.
- W2058432012 hasConceptScore W2058432012C71924100 @default.
- W2058432012 hasConceptScore W2058432012C98274493 @default.
- W2058432012 hasIssue "5" @default.
- W2058432012 hasLocation W20584320121 @default.
- W2058432012 hasLocation W20584320122 @default.
- W2058432012 hasOpenAccess W2058432012 @default.
- W2058432012 hasPrimaryLocation W20584320121 @default.
- W2058432012 hasRelatedWork W1542457874 @default.
- W2058432012 hasRelatedWork W1593543690 @default.
- W2058432012 hasRelatedWork W178726011 @default.
- W2058432012 hasRelatedWork W1941449931 @default.
- W2058432012 hasRelatedWork W2031191514 @default.
- W2058432012 hasRelatedWork W2086777616 @default.
- W2058432012 hasRelatedWork W2608516576 @default.
- W2058432012 hasRelatedWork W2920991951 @default.
- W2058432012 hasRelatedWork W3164156822 @default.
- W2058432012 hasRelatedWork W4313315104 @default.
- W2058432012 hasVolume "83" @default.
- W2058432012 isParatext "false" @default.
- W2058432012 isRetracted "false" @default.
- W2058432012 magId "2058432012" @default.
- W2058432012 workType "article" @default.