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• W2058458909 abstract "We examined whole blood (MnB), plasma (MnP) and urinary Mn (MnU) concentrations in 33 cirrhotics and 11 healthy controls to clarify: (1) whether, in chronic liver diseases, MnB or MnP reflects pallidal signal intensities in magnetic resonance imaging (MRI); and (2) which factors in chronic liver diseases correlate with pallidal signal intensities in T1-weighted MRI. Increased signal intensity in the pallidum was observed in 27 (81.8%) of 33 patients with liver cirrhosis in T1-weighted MRI. There was a significant correlation between MnB and pallidal index (PI) (γ = 0.559, P < 0.01) in the patients. However, no significant correlation was observed between MnP and PI (γ = 0.353, P > 0.05). According to a multiple linear regression, MnB reflected the signal intensities of T1-weighted MRI better than MnP or MnU. Child/Pugh score and total bilirubin level also correlated with PI. However, the hemoglobin level did not correlate with PI significantly." @default.
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• W2058458909 date "2003-12-01" @default.
• W2058458909 modified "2023-10-14" @default.
• W2058458909 title "Whole Blood Manganese Correlates with High Signal Intensities on T1-Weighted MRI in Patients with Liver Cirrhosis" @default.
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• W2058458909 doi "https://doi.org/10.1016/s0161-813x(03)00111-6" @default.
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