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- W2058461791 abstract "Abstract Sections of liver from normal and atherosclerotic rabbits, treated 5 to 8 weeks with daily subsequent heparin or saline injections, were examined. Both paraffin and epon sections stained with toluidine blue were observed. Metachromatic inclusions indicative of heparin were found in cells lining the liver sinusoids of heparin treated rabbits but not in similar cells of saline treated rabbits. Electronmicroscopic examination of sections adjacent to the thick epon sections indicated that these metachromatic inclusions were present in vacuoles of endothelial cells as well as Kupffer cells. This observation supports the existing evidence that the liver along with the reticuloendothelial system and endothelial cells play a role in the distribution of administered heparin." @default.
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- W2058461791 date "1981-02-01" @default.
- W2058461791 modified "2023-10-16" @default.
- W2058461791 title "The uptake of heparin by liver sinusoidal cells in normal and atherosclerotic rabbits" @default.
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- W2058461791 doi "https://doi.org/10.1016/0049-3848(81)90139-0" @default.
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