FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2058471523> ?p ?o ?g. }

• W2058471523 endingPage "196" @default.
• W2058471523 startingPage "187" @default.
• W2058471523 abstract "It has been proposed that exchange between membrane cholesterol pools occurs by desorption of molecules into the aqueous environment rather than by formation of a transitory collision complex between the membranes. The rate of exchange is likely to be determined by the rate of dissociation of cholesterol from the membrane bilayer and by the concentration of cholesterol monomers or aggregates of cholesterol molecules in solution. The aim of this study was to measure the effects of agents known to increase cholesterol exchange rates on cholesterol solubility, critical micellar concentration and on the activation energy of exchange. A comparison was also made with regard to these parameters, of the exchange of cholesterol to that of 4-cholesten-3-one, another steroid which exchanges more rapidly than cholesterol. Acetone and dimethylsulphoxide increased cholesterol exchange between liposomes and erythrocytes, but only modestly increased the apparent solubility of cholesterol in saline and had no effect on the activation energy of the exchange process. However, acetone and dimethylsulphoxide increased the critical micellar concentration of the cholesterol 3-fold, although tetraethylammonium iodide, which had a smaller effect on exchange, did not. 4-Cholesten-3-one had a lower solubility and critical micellar concentration than that of cholesterol, but had the same activation energy for exchange. It is concluded that the apparent solubility of steroid aggregates are unlikely to determine the rate of exchange, but that agents which substantially increase exchange also increase the critical micellar concentration. The low critical micellar concentration of cholestenone suggests that the actual monomer concentration in an exchange system is low and that the rate of dissociation of the molecules from the liposomes must determine the exchange rate. This is not reflected in the activation energy measurements since these are a composite of all the elements of the exchange process." @default.
• W2058471523 created "2016-06-24" @default.
• W2058471523 creator A5051860801 @default.
• W2058471523 creator A5085185873 @default.
• W2058471523 date "1984-01-01" @default.
• W2058471523 modified "2023-09-27" @default.
• W2058471523 title "The solubility of cholesterol and its exchange between membranes" @default.
• W2058471523 cites W1513897103 @default.
• W2058471523 cites W1515048140 @default.
• W2058471523 cites W1533285881 @default.
• W2058471523 cites W1882704643 @default.
• W2058471523 cites W1972617850 @default.
• W2058471523 cites W1987697559 @default.
• W2058471523 cites W1989476508 @default.
• W2058471523 cites W1993805810 @default.
• W2058471523 cites W1998586897 @default.
• W2058471523 cites W2003456498 @default.
• W2058471523 cites W2005277127 @default.
• W2058471523 cites W2015821566 @default.
• W2058471523 cites W2017484470 @default.
• W2058471523 cites W2025761051 @default.
• W2058471523 cites W2026303867 @default.
• W2058471523 cites W2041304269 @default.
• W2058471523 cites W2043483779 @default.
• W2058471523 cites W2043713555 @default.
• W2058471523 cites W2049266592 @default.
• W2058471523 cites W2080644290 @default.
• W2058471523 cites W2097174011 @default.
• W2058471523 cites W2104010651 @default.
• W2058471523 cites W2116026746 @default.
• W2058471523 cites W2151571897 @default.
• W2058471523 cites W2152311269 @default.
• W2058471523 cites W2154995837 @default.
• W2058471523 cites W2168526937 @default.
• W2058471523 cites W2169542805 @default.
• W2058471523 cites W2323304304 @default.
• W2058471523 cites W2399943115 @default.
• W2058471523 doi "https://doi.org/10.1016/0005-2736(84)90022-1" @default.
• W2058471523 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6691973" @default.
• W2058471523 hasPublicationYear "1984" @default.
• W2058471523 type Work @default.
• W2058471523 sameAs 2058471523 @default.
• W2058471523 citedByCount "43" @default.
• W2058471523 countsByYear W20584715232014 @default.
• W2058471523 countsByYear W20584715232016 @default.
• W2058471523 crossrefType "journal-article" @default.
• W2058471523 hasAuthorship W2058471523A5051860801 @default.
• W2058471523 hasAuthorship W2058471523A5085185873 @default.
• W2058471523 hasConcept C102931765 @default.
• W2058471523 hasConcept C155574463 @default.
• W2058471523 hasConcept C178790620 @default.
• W2058471523 hasConcept C184651966 @default.
• W2058471523 hasConcept C185592680 @default.
• W2058471523 hasConcept C2778163477 @default.
• W2058471523 hasConcept C41625074 @default.
• W2058471523 hasConcept C43617362 @default.
• W2058471523 hasConcept C55493867 @default.
• W2058471523 hasConceptScore W2058471523C102931765 @default.
• W2058471523 hasConceptScore W2058471523C155574463 @default.
• W2058471523 hasConceptScore W2058471523C178790620 @default.
• W2058471523 hasConceptScore W2058471523C184651966 @default.
• W2058471523 hasConceptScore W2058471523C185592680 @default.
• W2058471523 hasConceptScore W2058471523C2778163477 @default.
• W2058471523 hasConceptScore W2058471523C41625074 @default.
• W2058471523 hasConceptScore W2058471523C43617362 @default.
• W2058471523 hasConceptScore W2058471523C55493867 @default.
• W2058471523 hasIssue "1" @default.
• W2058471523 hasLocation W20584715231 @default.
• W2058471523 hasLocation W20584715232 @default.
• W2058471523 hasOpenAccess W2058471523 @default.
• W2058471523 hasPrimaryLocation W20584715231 @default.
• W2058471523 hasRelatedWork W1971893904 @default.
• W2058471523 hasRelatedWork W2009823598 @default.
• W2058471523 hasRelatedWork W2040146024 @default.
• W2058471523 hasRelatedWork W2084503887 @default.
• W2058471523 hasRelatedWork W2949080510 @default.
• W2058471523 hasRelatedWork W2951261188 @default.
• W2058471523 hasRelatedWork W2951280107 @default.
• W2058471523 hasRelatedWork W2951314393 @default.
• W2058471523 hasRelatedWork W2951570289 @default.
• W2058471523 hasRelatedWork W2952785262 @default.
• W2058471523 hasVolume "769" @default.
• W2058471523 isParatext "false" @default.
• W2058471523 isRetracted "false" @default.
• W2058471523 magId "2058471523" @default.
• W2058471523 workType "article" @default.