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• W2058482732 abstract "By the elucidation of high-resolution structures the view of the bioenergetic processes has become more precise. But in the face of these fundamental advances, many problems are still unresolved. We have examined a variety of aspects of energy-transducing membranes from large protein complexes down to the level of protons and functional relevant picosecond protein dynamics. Based on the central role of the ATP synthase for supplying the biological fuel ATP, one main emphasis was put on this protein complex from both chloroplast and mitochondria. In particular the stoichiometry of protons required for the synthesis of one ATP molecule and the supramolecular organisation of ATP synthases were examined. Since formation of supercomplexes also concerns other complexes of the respiratory chain, our work was directed to unravel this kind of organisation, e.g. of the OXPHOS supercomplex I(1)III(2)IV(1), in terms of structure and function. Not only the large protein complexes or supercomplexes work as key players for biological energy conversion, but also small components as quinones which facilitate the transfer of electrons and protons. Therefore, their location in the membrane profile was determined by neutron diffraction. Physico-chemical features of the path of protons from the generators of the electrochemical gradient to the ATP synthase, as well as of their interaction with the membrane surface, could be elucidated by time-resolved absorption spectroscopy in combination with optical pH indicators. Diseases such as Alzheimer's dementia (AD) are triggered by perturbation of membranes and bioenergetics as demonstrated by our neutron scattering studies." @default.
• W2058482732 created "2016-06-24" @default.
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• W2058482732 date "2009-06-01" @default.
• W2058482732 modified "2023-10-03" @default.
• W2058482732 title "From protons to OXPHOS supercomplexes and Alzheimer's disease: Structure–dynamics–function relationships of energy-transducing membranes" @default.
• W2058482732 cites W143268885 @default.
• W2058482732 cites W1500862847 @default.
• W2058482732 cites W1505393044 @default.
• W2058482732 cites W1524847237 @default.
• W2058482732 cites W1555985610 @default.
• W2058482732 cites W1591326119 @default.
• W2058482732 cites W1606935319 @default.
• W2058482732 cites W1837184912 @default.
• W2058482732 cites W1858651405 @default.
• W2058482732 cites W1964051078 @default.
• W2058482732 cites W1964126982 @default.
• W2058482732 cites W1966728800 @default.
• W2058482732 cites W1967450606 @default.
• W2058482732 cites W1967461021 @default.
• W2058482732 cites W1967888351 @default.
• W2058482732 cites W1969978376 @default.
• W2058482732 cites W1974279757 @default.
• W2058482732 cites W1978076941 @default.
• W2058482732 cites W1979542564 @default.
• W2058482732 cites W1980825524 @default.
• W2058482732 cites W1982645175 @default.
• W2058482732 cites W1982692501 @default.
• W2058482732 cites W1982840514 @default.
• W2058482732 cites W1983737836 @default.
• W2058482732 cites W1985074623 @default.
• W2058482732 cites W1985411745 @default.
• W2058482732 cites W1988431659 @default.
• W2058482732 cites W1988844499 @default.
• W2058482732 cites W1989021530 @default.
• W2058482732 cites W1989176019 @default.
• W2058482732 cites W1993033824 @default.
• W2058482732 cites W1993622331 @default.
• W2058482732 cites W1994220380 @default.
• W2058482732 cites W1996917933 @default.
• W2058482732 cites W1997303616 @default.
• W2058482732 cites W1997666076 @default.
• W2058482732 cites W1998098749 @default.
• W2058482732 cites W1999671103 @default.
• W2058482732 cites W2000375746 @default.
• W2058482732 cites W2000794984 @default.
• W2058482732 cites W2000809937 @default.
• W2058482732 cites W2001254662 @default.
• W2058482732 cites W2001806196 @default.
• W2058482732 cites W2002725375 @default.
• W2058482732 cites W2004762714 @default.
• W2058482732 cites W2005769249 @default.
• W2058482732 cites W2007047564 @default.
• W2058482732 cites W2008003969 @default.
• W2058482732 cites W2008239934 @default.
• W2058482732 cites W2008929188 @default.
• W2058482732 cites W2011745910 @default.
• W2058482732 cites W2011967974 @default.
• W2058482732 cites W2017523584 @default.
• W2058482732 cites W2018607050 @default.
• W2058482732 cites W2019169693 @default.
• W2058482732 cites W2021467041 @default.
• W2058482732 cites W2022211687 @default.
• W2058482732 cites W2022328488 @default.
• W2058482732 cites W2025397222 @default.
• W2058482732 cites W2025499001 @default.
• W2058482732 cites W2028538125 @default.
• W2058482732 cites W2029663082 @default.
• W2058482732 cites W2030002442 @default.
• W2058482732 cites W2030086654 @default.
• W2058482732 cites W2031227547 @default.
• W2058482732 cites W2033386994 @default.
• W2058482732 cites W2033619355 @default.
• W2058482732 cites W2034916027 @default.
• W2058482732 cites W2035644592 @default.
• W2058482732 cites W2035817126 @default.
• W2058482732 cites W2038724151 @default.
• W2058482732 cites W2038981375 @default.
• W2058482732 cites W2039254203 @default.
• W2058482732 cites W2039646555 @default.
• W2058482732 cites W2041398967 @default.
• W2058482732 cites W2044414180 @default.
• W2058482732 cites W2047504083 @default.
• W2058482732 cites W2048427215 @default.
• W2058482732 cites W2049638544 @default.
• W2058482732 cites W2052423689 @default.

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