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• W2058485982 abstract "In three moderately hypercapnic men (e~35 L/min) repeated exposure to sudden transient hypocapnia induced depression of e after 2–3 breaths (?arterial chemoreceptor response) in mild lypoxia (PaO2 ~63 torr) but only after 5 breaths ( ?intracranial chemoreceptor response) in hyperoxia Pao2 ~ 650 torr). Sudden relief of hypoxia (hypercapnia maintained) depressed e after 3–4 breaths ( ∼ 100 tests of each kind). Usually Vt changed more and f changed less than with corresponding steady-state changes of e. Thus (1) human arterial chemoreceptors respond more quickly to change of CO2 than of hypoxia, and (2) hypoxia is a prerequisite for the response of human arterial chemoreceptors to CO2: hypoxic-hypercapnic interaction is largely peripheral." @default.
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• W2058485982 date "1974-02-01" @default.
• W2058485982 modified "2023-09-27" @default.
• W2058485982 title "The transient respiratory effects in man of sudden changes in alveolar CO2, in hypoxia and in high oxygen" @default.
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• W2058485982 doi "https://doi.org/10.1016/0034-5687(74)90015-2" @default.
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