FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2058506110> ?p ?o ?g. }

• W2058506110 endingPage "675" @default.
• W2058506110 startingPage "669" @default.
• W2058506110 abstract "Objectives To evaluate the impact of the endothelial nitric oxide synthase (eNOS) gene on longitudinal development of blood pressure (BP) and left ventricular mass (LVM) from childhood into early adulthood. Methods Three polymorphisms including −922A>G, intron 4VNTR, and Glu298Asp of the eNOS gene were investigated. Individual growth-curve modeling and haplotype trend regression analyses were conducted for 579 white and black American youths with 12 assessments over a 15-year period. Results Significantly different allele and genotype frequencies were observed between blacks and whites for all three polymorphisms. Linkage disequilibrium (LD) patterns among these polymorphisms were also different between ethnic groups: strong LD between the −922A>G and intron 4 VNTR loci was observed in whites but not in blacks. Single locus analyses identified a significant interaction between the intron 4 VNTR and gender on diastolic BP (DBP) levels. The 4a allele carriers had significantly lower DBP levels in males (P=0.012), but higher DBP levels in females (P=0.045). Haplotype analyses confirmed the DBP lowering effect in males (P=0.049). DBP in males homozygous for haplotype G-4a-Glu was 2.58 mmHg lower than males homozygous for the most common haplotype (A-non4a-Glu). Additionally, individuals homozygous for haplotype G-non4a-Glu showed a 0.51 mmHg steeper increase in DBP per year with age as compared to the most common haplotype (P=0.007). No associations between single polymorphisms or haplotypes of the eNOS gene and systolic BP or LVM were found. Conclusions our results suggest that eNOS gene may have gender-specific and age-dependent effects on DBP and the development of hypertension risk." @default.
• W2058506110 created "2016-06-24" @default.
• W2058506110 creator A5006009860 @default.
• W2058506110 creator A5017557616 @default.
• W2058506110 creator A5027571680 @default.
• W2058506110 creator A5029432337 @default.
• W2058506110 creator A5055589821 @default.
• W2058506110 date "2005-09-01" @default.
• W2058506110 modified "2023-09-27" @default.
• W2058506110 title "Influence of the eNOS gene on development of blood pressure and left ventricular mass: Longitudinal findings in multiethnic youth" @default.
• W2058506110 cites W1972561326 @default.
• W2058506110 cites W1994640204 @default.
• W2058506110 cites W1996913485 @default.
• W2058506110 cites W2008085210 @default.
• W2058506110 cites W2009452775 @default.
• W2058506110 cites W2018550467 @default.
• W2058506110 cites W2020336883 @default.
• W2058506110 cites W2024002735 @default.
• W2058506110 cites W2028142113 @default.
• W2058506110 cites W2032201224 @default.
• W2058506110 cites W2038129786 @default.
• W2058506110 cites W2040580851 @default.
• W2058506110 cites W2040901946 @default.
• W2058506110 cites W2041781505 @default.
• W2058506110 cites W2042293234 @default.
• W2058506110 cites W2044245639 @default.
• W2058506110 cites W2075178407 @default.
• W2058506110 cites W2076795933 @default.
• W2058506110 cites W2080766847 @default.
• W2058506110 cites W2083878136 @default.
• W2058506110 cites W2089435493 @default.
• W2058506110 cites W2091193879 @default.
• W2058506110 cites W2095965506 @default.
• W2058506110 cites W2101435121 @default.
• W2058506110 cites W2104486246 @default.
• W2058506110 cites W2110229656 @default.
• W2058506110 cites W2113220448 @default.
• W2058506110 cites W2119093576 @default.
• W2058506110 cites W2119266889 @default.
• W2058506110 cites W2124284996 @default.
• W2058506110 cites W2124709306 @default.
• W2058506110 cites W2128365184 @default.
• W2058506110 cites W2136666054 @default.
• W2058506110 cites W2140068354 @default.
• W2058506110 cites W2140982717 @default.
• W2058506110 cites W2141719916 @default.
• W2058506110 cites W2144024299 @default.
• W2058506110 cites W2148174695 @default.
• W2058506110 cites W2148603659 @default.
• W2058506110 cites W2149749492 @default.
• W2058506110 cites W2157155755 @default.
• W2058506110 cites W2159970886 @default.
• W2058506110 cites W2166322166 @default.
• W2058506110 cites W2169502478 @default.
• W2058506110 cites W2319460905 @default.
• W2058506110 cites W2341645956 @default.
• W2058506110 cites W2990123797 @default.
• W2058506110 doi "https://doi.org/10.1097/01.fpc.0000172244.65417.7a" @default.
• W2058506110 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16041245" @default.
• W2058506110 hasPublicationYear "2005" @default.
• W2058506110 type Work @default.
• W2058506110 sameAs 2058506110 @default.
• W2058506110 citedByCount "26" @default.
• W2058506110 countsByYear W20585061102012 @default.
• W2058506110 countsByYear W20585061102013 @default.
• W2058506110 countsByYear W20585061102014 @default.
• W2058506110 countsByYear W20585061102015 @default.
• W2058506110 countsByYear W20585061102017 @default.
• W2058506110 countsByYear W20585061102018 @default.
• W2058506110 countsByYear W20585061102019 @default.
• W2058506110 crossrefType "journal-article" @default.
• W2058506110 hasAuthorship W2058506110A5006009860 @default.
• W2058506110 hasAuthorship W2058506110A5017557616 @default.
• W2058506110 hasAuthorship W2058506110A5027571680 @default.
• W2058506110 hasAuthorship W2058506110A5029432337 @default.
• W2058506110 hasAuthorship W2058506110A5055589821 @default.
• W2058506110 hasConcept C104317684 @default.
• W2058506110 hasConcept C126322002 @default.
• W2058506110 hasConcept C134018914 @default.
• W2058506110 hasConcept C135763542 @default.
• W2058506110 hasConcept C180754005 @default.
• W2058506110 hasConcept C197754878 @default.
• W2058506110 hasConcept C2777622882 @default.
• W2058506110 hasConcept C2778326061 @default.
• W2058506110 hasConcept C2780221984 @default.
• W2058506110 hasConcept C35605836 @default.
• W2058506110 hasConcept C37463918 @default.
• W2058506110 hasConcept C519581460 @default.
• W2058506110 hasConcept C54355233 @default.
• W2058506110 hasConcept C71924100 @default.
• W2058506110 hasConcept C84393581 @default.
• W2058506110 hasConcept C86803240 @default.
• W2058506110 hasConceptScore W2058506110C104317684 @default.
• W2058506110 hasConceptScore W2058506110C126322002 @default.
• W2058506110 hasConceptScore W2058506110C134018914 @default.
• W2058506110 hasConceptScore W2058506110C135763542 @default.
• W2058506110 hasConceptScore W2058506110C180754005 @default.
• W2058506110 hasConceptScore W2058506110C197754878 @default.

• next