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- W2058508701 abstract "Normally cycling ewes were treated with intramuscular injections of either progesterone or estradiol dipropionate. Daily injections of progesterone (50 mg in oil) diminished the amount of oxytocin that appeared in jugular vein blood when the vagina was distended with an air-filled balloon. Before treatment, distention increased plasma oxytocin from a prestimulated level of 7 + 1 (mean ±se) to 24 ± 6 μU/ml. After 1 week, the plasma oxytocin level increased from 6 ± 1 to 15 ± 8 μU/ml when the vagina was distended. After 2 weeks of progesterone treatment, no significant increase in plasma oxytocin occurred during the vaginal distention. On the other hand, twice weekly injections of estradiol dipropionate led to marked elevations in the amount of oxytocin appearing in the blood during vaginal distention. From a resting level of 5 ± 1 μU/ml, stimulation increased plasma oxytocin concentration to 87 ± 16 μU/ml in animals treated for 1 week and to 138 ± 53 μU/ml in animals treated for 2 weeks. Several interpreta..." @default.
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- W2058508701 date "1969-05-01" @default.
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- W2058508701 title "Effects of Progesterone and Estrogen on Blood Levels of Oxytocin During Vaginal Distention" @default.
- W2058508701 doi "https://doi.org/10.1210/endo-84-5-1076" @default.
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