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- W2058516828 abstract "The mechanisms responsible for changes in T wave symmetry and amplitude with changes in heart rate and action potential duration were investigated. A computer model of normal left ventricular repolarization was used to simulate the T waves on the surface 12-lead ECG. The effect of heart rate changes was studied by varying the ratio between dispersion of repolarization (Disp) and action potential repolarization duration (APRD). With constant dispersion, as heart rate increases, APRD decreases and the ratio Disp/APRD increases. T waves were simulated while varying the Disp/APRD ratio from 3.6% to 100%. The T wave symmetry ratio measured from the areas either side of the peak (SRarea), the symmetry ratio from the times either side of the peak (SRtime) and the T wave amplitude (Tamplitude) were calculated from each simulated ECG. SRarea decreased from 1.42 to 0.77, SRtime from 1.75 to 1.04 and the Tamplitude increased from 0.19 mV to 2.30 mV." @default.
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- W2058516828 date "2002-03-08" @default.
- W2058516828 modified "2023-10-18" @default.
- W2058516828 title "Effect of changes in heart rate and in action potential duration on the electrocardiogram T wave shape" @default.
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- W2058516828 doi "https://doi.org/10.1088/0967-3334/23/2/311" @default.
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