FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2058525313> ?p ?o ?g. }

• W2058525313 endingPage "231" @default.
• W2058525313 startingPage "219" @default.
• W2058525313 abstract "The antigen expression profiles of Mycoplasma gallisepticum isolates obtained from tracheal swabs of chickens after aerosol-inoculation with M. gallisepticum strain R or clonal variant RE were examined in western immunoblots. A reference anti-M. gallisepticum chicken antiserum and antisera from individual infected chickens as well as monoclonal antibodies (mAbs) specific for surface proteins were used to monitor in vivo antigenic variation. mAbs 1E5 and 12D8, recognizing PvpA and p67a, recently shown to undergo high-frequency in vitro phase variation, were used for consecutive staining of colony and western immunoblots in order to distinguish between the resultant phenotypes with respect to the corresponding epitopes. Marked differences in the expression of major immunogenic proteins, including p67a, were observed between the two inocula as well as among reisolates recovered at different times of infection. Comparative western immunoblot analysis of the rapidly changing chicken serum antibody response and reisolates recovered during the course of an experimental infection with M. gallisepticum R or clonal variant RE suggest that immune modulation may have a key role in generating surface diversity. In addition, comparison of colony immunoblots of strain R inoculum and of reisolated colonies from tracheas of birds 8 days post infection indicated an in vivo selection of the PvpA+p67a− phenotype. This study established that surface antigens of M. gallisepticum are subjected in vivo to rapid alteration in their expression. This variability may function as a crucial adaptive mechanism, enabling the organism to escape from the host immune defense and to adapt to the changing host evironment at different stages of a natural infection." @default.
• W2058525313 created "2016-06-24" @default.
• W2058525313 creator A5018064327 @default.
• W2058525313 creator A5076864812 @default.
• W2058525313 creator A5089184848 @default.
• W2058525313 date "1995-07-01" @default.
• W2058525313 modified "2023-09-23" @default.
• W2058525313 title "In vivo variation of Mycoplasma gallisepticum antigen expression in experimentally infected chickens" @default.
• W2058525313 cites W176652973 @default.
• W2058525313 cites W1832831785 @default.
• W2058525313 cites W1884002966 @default.
• W2058525313 cites W1901042476 @default.
• W2058525313 cites W2016374428 @default.
• W2058525313 cites W2043638041 @default.
• W2058525313 cites W2049038958 @default.
• W2058525313 cites W2056560026 @default.
• W2058525313 cites W2081453080 @default.
• W2058525313 cites W2087993813 @default.
• W2058525313 cites W2095381278 @default.
• W2058525313 cites W2095607888 @default.
• W2058525313 cites W2101836156 @default.
• W2058525313 cites W2107641291 @default.
• W2058525313 cites W2147343476 @default.
• W2058525313 cites W2168120932 @default.
• W2058525313 cites W2320174124 @default.
• W2058525313 cites W2325182496 @default.
• W2058525313 cites W2328784949 @default.
• W2058525313 cites W2330756460 @default.
• W2058525313 cites W4300112511 @default.
• W2058525313 doi "https://doi.org/10.1016/0378-1135(95)00039-d" @default.
• W2058525313 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7571373" @default.
• W2058525313 hasPublicationYear "1995" @default.
• W2058525313 type Work @default.
• W2058525313 sameAs 2058525313 @default.
• W2058525313 citedByCount "59" @default.
• W2058525313 countsByYear W20585253132012 @default.
• W2058525313 countsByYear W20585253132013 @default.
• W2058525313 countsByYear W20585253132015 @default.
• W2058525313 countsByYear W20585253132017 @default.
• W2058525313 countsByYear W20585253132018 @default.
• W2058525313 countsByYear W20585253132019 @default.
• W2058525313 countsByYear W20585253132020 @default.
• W2058525313 countsByYear W20585253132021 @default.
• W2058525313 countsByYear W20585253132022 @default.
• W2058525313 crossrefType "journal-article" @default.
• W2058525313 hasAuthorship W2058525313A5018064327 @default.
• W2058525313 hasAuthorship W2058525313A5076864812 @default.
• W2058525313 hasAuthorship W2058525313A5089184848 @default.
• W2058525313 hasConcept C147483822 @default.
• W2058525313 hasConcept C159047783 @default.
• W2058525313 hasConcept C159654299 @default.
• W2058525313 hasConcept C191942190 @default.
• W2058525313 hasConcept C195616568 @default.
• W2058525313 hasConcept C203014093 @default.
• W2058525313 hasConcept C207001950 @default.
• W2058525313 hasConcept C2775881110 @default.
• W2058525313 hasConcept C2777233064 @default.
• W2058525313 hasConcept C2778838687 @default.
• W2058525313 hasConcept C2781151156 @default.
• W2058525313 hasConcept C542903549 @default.
• W2058525313 hasConcept C54355233 @default.
• W2058525313 hasConcept C86803240 @default.
• W2058525313 hasConcept C8891405 @default.
• W2058525313 hasConcept C89423630 @default.
• W2058525313 hasConcept C91523082 @default.
• W2058525313 hasConceptScore W2058525313C147483822 @default.
• W2058525313 hasConceptScore W2058525313C159047783 @default.
• W2058525313 hasConceptScore W2058525313C159654299 @default.
• W2058525313 hasConceptScore W2058525313C191942190 @default.
• W2058525313 hasConceptScore W2058525313C195616568 @default.
• W2058525313 hasConceptScore W2058525313C203014093 @default.
• W2058525313 hasConceptScore W2058525313C207001950 @default.
• W2058525313 hasConceptScore W2058525313C2775881110 @default.
• W2058525313 hasConceptScore W2058525313C2777233064 @default.
• W2058525313 hasConceptScore W2058525313C2778838687 @default.
• W2058525313 hasConceptScore W2058525313C2781151156 @default.
• W2058525313 hasConceptScore W2058525313C542903549 @default.
• W2058525313 hasConceptScore W2058525313C54355233 @default.
• W2058525313 hasConceptScore W2058525313C86803240 @default.
• W2058525313 hasConceptScore W2058525313C8891405 @default.
• W2058525313 hasConceptScore W2058525313C89423630 @default.
• W2058525313 hasConceptScore W2058525313C91523082 @default.
• W2058525313 hasIssue "2-3" @default.
• W2058525313 hasLocation W20585253131 @default.
• W2058525313 hasLocation W20585253132 @default.
• W2058525313 hasOpenAccess W2058525313 @default.
• W2058525313 hasPrimaryLocation W20585253131 @default.
• W2058525313 hasRelatedWork W1604248381 @default.
• W2058525313 hasRelatedWork W1929434617 @default.
• W2058525313 hasRelatedWork W2026978417 @default.
• W2058525313 hasRelatedWork W2034184054 @default.
• W2058525313 hasRelatedWork W2058525313 @default.
• W2058525313 hasRelatedWork W2081292628 @default.
• W2058525313 hasRelatedWork W2161382308 @default.
• W2058525313 hasRelatedWork W2324329362 @default.
• W2058525313 hasRelatedWork W2327445981 @default.
• W2058525313 hasRelatedWork W2428781532 @default.
• W2058525313 hasVolume "45" @default.

• next