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- W2058550661 abstract "All patients admitted with severe lactic acidosis to a university teaching hospital during a 17-month period were taking phenformin hydrochloride. Serum phenformin concentration was measured in one patient and found to be four to nine times the usual therapeutic concentration. Prerenal azotemia was present at the time of admission in all but one of these patients, but renal function was normal at the time of discharge in those patients with phenformin-associated lactic acidosis who survived. Phenformin-associated lactic acidosis accounted for 7% of the episodes of metabolic acidosis and 27% of deaths due to metabolic acidosis in diabetics." @default.
- W2058550661 created "2016-06-24" @default.
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- W2058550661 date "1976-04-12" @default.
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- W2058550661 title "Phenformin and Lactic Acidosis" @default.
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- W2058550661 doi "https://doi.org/10.1001/jama.1976.03260410031019" @default.
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