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• W2058553510 abstract "Coronary artery disease and acute myocardial infarction (AMI) are the leading causes of death for both men and women. Serum cardiac-specific troponin level is now used for the early diagnosis of AMI. However, due to the delayed release of troponin, an earlier, more sensitive and specific biomarker is urgently demanded to further reduce AMI mortality. Recent studies have found that circulating microRNAs (miRNAs) are closely linked to myocardial injury. Due to the cell-specific physiological functions and the stability of miRNAs in plasma, serum, and urine, they are emerging as sensitive biomarkers of AMI. This review summarizes the latest insights into the identification and potential application of plasma and serum miRNAs as novel biomarkers for diagnosis and prognosis of AMI." @default.
• W2058553510 created "2016-06-24" @default.
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• W2058553510 date "2012-07-01" @default.
• W2058553510 modified "2023-10-17" @default.
• W2058553510 title "Circulating microRNAs as novel and sensitive biomarkers of acute myocardial Infarction" @default.
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• W2058553510 doi "https://doi.org/10.1016/j.clinbiochem.2012.04.013" @default.
• W2058553510 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3965350" @default.
• W2058553510 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22713968" @default.
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