FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2058558306> ?p ?o ?g. }

• W2058558306 endingPage "284" @default.
• W2058558306 startingPage "275" @default.
• W2058558306 abstract "The effects of an adenovirus-mediated Bcl-X(L) expression, driven by a neuron-specific human synapsin-1 promoter, on the degree of injury, were examined after transient focal ischemia in mice. Therefore, injections of vehicle, of an adenoviral E1-deleted control vector (Ad-dE1), or a Bcl-X(L) vector (Ad-Syn-Bcl-X(L)) were stereotactically made in the striatum. Seven days later, focal ischemia was induced either by 30 min or 2 h of intraluminal thread occlusion. In line with previous data, 30 min of middle cerebral artery (MCA) occlusion reproducibly resulted in disseminated neuronal injury of the striatum, as revealed by cresyl violet and TUNEL 3 days after ischemia. The degree of cell injury was significantly reduced in Ad-Syn-Bcl-X(L) treated as compared with Ad-dE1 and vehicle-treated animals. On the other hand, 2 h of MCA occlusion produced reproducible infarcts both in vehicle and Ad-dE1 treated animals 24 h after ischemia. The infarct area at the level of the striatum was significantly decreased by Ad-Syn-Bcl-X(L) treatment. The present data demonstrate that an adenoviral Bcl-X(L) expression with a neuron-specific synapsin-1 promoter provides a powerful tool, which not only diminishes disseminated neuronal injury, but also protects against tissue infarction." @default.
• W2058558306 created "2016-06-24" @default.
• W2058558306 creator A5004664907 @default.
• W2058558306 creator A5012755593 @default.
• W2058558306 creator A5013141968 @default.
• W2058558306 creator A5016418059 @default.
• W2058558306 creator A5028410367 @default.
• W2058558306 creator A5050072898 @default.
• W2058558306 creator A5087490218 @default.
• W2058558306 date "2002-11-01" @default.
• W2058558306 modified "2023-10-10" @default.
• W2058558306 title "Adenovirus-Mediated Bcl-XL Expression Using a Neuron-Specific Synapsin-1 Promoter Protects against Disseminated Neuronal Injury and Brain Infarction Following Focal Cerebral Ischemia in Mice" @default.
• W2058558306 cites W1503813864 @default.
• W2058558306 cites W1529927626 @default.
• W2058558306 cites W1970283820 @default.
• W2058558306 cites W1978771460 @default.
• W2058558306 cites W1979761775 @default.
• W2058558306 cites W1983112915 @default.
• W2058558306 cites W1988887903 @default.
• W2058558306 cites W1998595310 @default.
• W2058558306 cites W1998903105 @default.
• W2058558306 cites W2015788325 @default.
• W2058558306 cites W2017082833 @default.
• W2058558306 cites W2018773565 @default.
• W2058558306 cites W2032221839 @default.
• W2058558306 cites W2032397428 @default.
• W2058558306 cites W2050942708 @default.
• W2058558306 cites W2059006262 @default.
• W2058558306 cites W2063057031 @default.
• W2058558306 cites W2063576193 @default.
• W2058558306 cites W2072140726 @default.
• W2058558306 cites W2088270787 @default.
• W2058558306 cites W2089202414 @default.
• W2058558306 cites W2164248223 @default.
• W2058558306 cites W2168496647 @default.
• W2058558306 cites W2168546520 @default.
• W2058558306 cites W2330277685 @default.
• W2058558306 doi "https://doi.org/10.1006/nbdi.2002.0552" @default.
• W2058558306 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12505420" @default.
• W2058558306 hasPublicationYear "2002" @default.
• W2058558306 type Work @default.
• W2058558306 sameAs 2058558306 @default.
• W2058558306 citedByCount "23" @default.
• W2058558306 countsByYear W20585583062012 @default.
• W2058558306 countsByYear W20585583062013 @default.
• W2058558306 countsByYear W20585583062014 @default.
• W2058558306 countsByYear W20585583062016 @default.
• W2058558306 countsByYear W20585583062022 @default.
• W2058558306 countsByYear W20585583062023 @default.
• W2058558306 crossrefType "journal-article" @default.
• W2058558306 hasAuthorship W2058558306A5004664907 @default.
• W2058558306 hasAuthorship W2058558306A5012755593 @default.
• W2058558306 hasAuthorship W2058558306A5013141968 @default.
• W2058558306 hasAuthorship W2058558306A5016418059 @default.
• W2058558306 hasAuthorship W2058558306A5028410367 @default.
• W2058558306 hasAuthorship W2058558306A5050072898 @default.
• W2058558306 hasAuthorship W2058558306A5087490218 @default.
• W2058558306 hasConcept C104317684 @default.
• W2058558306 hasConcept C126322002 @default.
• W2058558306 hasConcept C130316041 @default.
• W2058558306 hasConcept C142724271 @default.
• W2058558306 hasConcept C148785051 @default.
• W2058558306 hasConcept C169760540 @default.
• W2058558306 hasConcept C196795494 @default.
• W2058558306 hasConcept C204232928 @default.
• W2058558306 hasConcept C26987225 @default.
• W2058558306 hasConcept C2777798775 @default.
• W2058558306 hasConcept C2778794669 @default.
• W2058558306 hasConcept C2778820722 @default.
• W2058558306 hasConcept C2780062018 @default.
• W2058558306 hasConcept C32470452 @default.
• W2058558306 hasConcept C40767141 @default.
• W2058558306 hasConcept C41625074 @default.
• W2058558306 hasConcept C500558357 @default.
• W2058558306 hasConcept C50493954 @default.
• W2058558306 hasConcept C513476851 @default.
• W2058558306 hasConcept C541997718 @default.
• W2058558306 hasConcept C55493867 @default.
• W2058558306 hasConcept C71924100 @default.
• W2058558306 hasConcept C86803240 @default.
• W2058558306 hasConceptScore W2058558306C104317684 @default.
• W2058558306 hasConceptScore W2058558306C126322002 @default.
• W2058558306 hasConceptScore W2058558306C130316041 @default.
• W2058558306 hasConceptScore W2058558306C142724271 @default.
• W2058558306 hasConceptScore W2058558306C148785051 @default.
• W2058558306 hasConceptScore W2058558306C169760540 @default.
• W2058558306 hasConceptScore W2058558306C196795494 @default.
• W2058558306 hasConceptScore W2058558306C204232928 @default.
• W2058558306 hasConceptScore W2058558306C26987225 @default.
• W2058558306 hasConceptScore W2058558306C2777798775 @default.
• W2058558306 hasConceptScore W2058558306C2778794669 @default.
• W2058558306 hasConceptScore W2058558306C2778820722 @default.
• W2058558306 hasConceptScore W2058558306C2780062018 @default.
• W2058558306 hasConceptScore W2058558306C32470452 @default.
• W2058558306 hasConceptScore W2058558306C40767141 @default.
• W2058558306 hasConceptScore W2058558306C41625074 @default.
• W2058558306 hasConceptScore W2058558306C500558357 @default.
• W2058558306 hasConceptScore W2058558306C50493954 @default.

• next