FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2058586673> ?p ?o ?g. }

• W2058586673 endingPage "482" @default.
• W2058586673 startingPage "473" @default.
• W2058586673 abstract "Numerous studies have shown sex and/or estrous cycle differences in the acoustic startle reflex (ASR) and its prepulse inhibition (PPI) in humans and animals. However, few have examined the effects of hormone manipulations on these behaviors. This study paired gonadectomy (GDX) in adult male rats with testing for ASR and PPI at 2, 4, 9, 16, 23, 30 and 37 days after surgery. Initial studies of control, GDX and GDX rats given testosterone propionate revealed no group differences in PPI, but did reveal phasic facilitation of the ASR in GDX rats that was greatest on the first and final testing sessions and that was attenuated by testosterone. A second study addressing roles for estrogen and androgen signaling tested new control and GDX rats along with GDX rats given estradiol or the non-aromatizable androgen, 5-alpha-dihydrotestosterone and revealed no group differences in PPI, and increases in ASR in GDX rats that were largest during the first and final testing sessions and that were attenuated by both hormone replacements. However, while responses in GDX rats given testosterone were similar to those of controls, ASR in estradiol- and to a lesser extent in dihydrotestosterone-treated GDX rats were typically lower than in controls. This may suggest that hormone modulation of the ASR requires synergistic estrogen and androgen actions. In the male brain where this can be achieved by local steroid metabolism, the enzymes responsible, e.g., aromatase, could help identify loci in the startle circuitry that may be especially relevant for the hormone modulation observed." @default.
• W2058586673 created "2016-06-24" @default.
• W2058586673 creator A5000318351 @default.
• W2058586673 creator A5034183854 @default.
• W2058586673 creator A5054229629 @default.
• W2058586673 date "2007-02-01" @default.
• W2058586673 modified "2023-09-23" @default.
• W2058586673 title "On again, off again effects of gonadectomy on the acoustic startle reflex in adult male rats" @default.
• W2058586673 cites W1505441000 @default.
• W2058586673 cites W1754932253 @default.
• W2058586673 cites W1963951882 @default.
• W2058586673 cites W1975180862 @default.
• W2058586673 cites W1975909673 @default.
• W2058586673 cites W1976990817 @default.
• W2058586673 cites W1980535000 @default.
• W2058586673 cites W1982135114 @default.
• W2058586673 cites W1984305433 @default.
• W2058586673 cites W1986597714 @default.
• W2058586673 cites W1986859027 @default.
• W2058586673 cites W1990414759 @default.
• W2058586673 cites W1993706485 @default.
• W2058586673 cites W1995348909 @default.
• W2058586673 cites W1997431826 @default.
• W2058586673 cites W1998072745 @default.
• W2058586673 cites W2005749656 @default.
• W2058586673 cites W2007675051 @default.
• W2058586673 cites W2012604247 @default.
• W2058586673 cites W2019030518 @default.
• W2058586673 cites W2020603439 @default.
• W2058586673 cites W2023060892 @default.
• W2058586673 cites W2024394464 @default.
• W2058586673 cites W2026301654 @default.
• W2058586673 cites W2028147063 @default.
• W2058586673 cites W2028889380 @default.
• W2058586673 cites W2030889776 @default.
• W2058586673 cites W2035307878 @default.
• W2058586673 cites W2035749259 @default.
• W2058586673 cites W2042871946 @default.
• W2058586673 cites W2046570248 @default.
• W2058586673 cites W2047187993 @default.
• W2058586673 cites W2050307219 @default.
• W2058586673 cites W2050581082 @default.
• W2058586673 cites W2051360697 @default.
• W2058586673 cites W2051896633 @default.
• W2058586673 cites W2055082059 @default.
• W2058586673 cites W2055433370 @default.
• W2058586673 cites W2065856183 @default.
• W2058586673 cites W2066322085 @default.
• W2058586673 cites W2066839027 @default.
• W2058586673 cites W2073113115 @default.
• W2058586673 cites W2073976265 @default.
• W2058586673 cites W2074132525 @default.
• W2058586673 cites W2079730191 @default.
• W2058586673 cites W2083579420 @default.
• W2058586673 cites W2089162657 @default.
• W2058586673 cites W2090979638 @default.
• W2058586673 cites W2102170600 @default.
• W2058586673 cites W2112593299 @default.
• W2058586673 cites W2122870641 @default.
• W2058586673 cites W2158339822 @default.
• W2058586673 cites W2159648246 @default.
• W2058586673 cites W2160249470 @default.
• W2058586673 cites W2163389230 @default.
• W2058586673 cites W4231844675 @default.
• W2058586673 cites W4232223103 @default.
• W2058586673 cites W4252436151 @default.
• W2058586673 doi "https://doi.org/10.1016/j.physbeh.2006.10.010" @default.
• W2058586673 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2517218" @default.
• W2058586673 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17169383" @default.
• W2058586673 hasPublicationYear "2007" @default.
• W2058586673 type Work @default.
• W2058586673 sameAs 2058586673 @default.
• W2058586673 citedByCount "20" @default.
• W2058586673 countsByYear W20585866732012 @default.
• W2058586673 countsByYear W20585866732013 @default.
• W2058586673 countsByYear W20585866732014 @default.
• W2058586673 countsByYear W20585866732018 @default.
• W2058586673 countsByYear W20585866732020 @default.
• W2058586673 countsByYear W20585866732022 @default.
• W2058586673 crossrefType "journal-article" @default.
• W2058586673 hasAuthorship W2058586673A5000318351 @default.
• W2058586673 hasAuthorship W2058586673A5034183854 @default.
• W2058586673 hasAuthorship W2058586673A5054229629 @default.
• W2058586673 hasBestOaLocation W20585866732 @default.
• W2058586673 hasConcept C118552586 @default.
• W2058586673 hasConcept C126322002 @default.
• W2058586673 hasConcept C134018914 @default.
• W2058586673 hasConcept C137431309 @default.
• W2058586673 hasConcept C141421786 @default.
• W2058586673 hasConcept C15744967 @default.
• W2058586673 hasConcept C2776412080 @default.
• W2058586673 hasConcept C2777164284 @default.
• W2058586673 hasConcept C2777911890 @default.
• W2058586673 hasConcept C2779279991 @default.
• W2058586673 hasConcept C2779881493 @default.
• W2058586673 hasConcept C2781115071 @default.
• W2058586673 hasConcept C2910993415 @default.
• W2058586673 hasConcept C71315377 @default.

• next