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- W2058640270 abstract "Desethylamiodarone has been identified as the principal lipophilic metabolite of amiodarone present in plasma specimens from amiodarone-treated patients. This structure has been confirmed by probe-injection mass spectrometry of column effluent fractions and comparison with the authentic compound using both chromatographic and mass spectrometric techniques. Although there is no information available as to the pharmacological activity of desethylamiodarone in man, the plasma concentrations of this metabolite attained during chronic amiodarone therapy are similar to those of the parent compound (0.1-4 mg litre-1)." @default.
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- W2058640270 date "1982-10-01" @default.
- W2058640270 modified "2023-09-27" @default.
- W2058640270 title "Identification and measurement of desethylamiodarone in blood plasma specimens from amiodarone-treated patients" @default.
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- W2058640270 doi "https://doi.org/10.1111/j.2042-7158.1982.tb04692.x" @default.
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