Matches in SemOpenAlex for { <https://semopenalex.org/work/W2058671732> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2058671732 endingPage "20" @default.
- W2058671732 startingPage "13" @default.
- W2058671732 abstract "Objective: In a potential attempt to guide antibiotic prescribing based on current clinical evidence and mitigate the spread of antibiotic resistance, in March 2001 the Ontario Drug Benefit programme restricted reimbursement of two fluoroquinolone antibiotics – ciprofloxacin and ofloxacin – to its beneficiaries. Our objective was to determine the impact of this policy on the volume and cost of antibiotic prescribing. Method: Weekly administrative data on antibiotic prescribing volumes and expenditures were analysed between January 1999 and September 2002 to estimate the effect of the policy changes using time series analysis. Results: The policy changes were associated with a statistically significant shift downwards for the fluoroquinolones as a category (1905 fewer prescriptions each week, representing a saving of Can$105,707 a week), driven by a decrease in prescriptions for ciprofloxacin (2084 fewer prescriptions a week, saving Can$129,421 a week). Nitrofurantoin (200 more prescriptions a week, costing an extra Can$2082 a week) and trimethoprim-sulphamethoxazole (532 more prescriptions a week, costing an extra Can$1473 a week) demonstrated a statistically significant shift upwards. The latter also showed a decrease in trend and nitrofurantoin an increase in trend during the time period. There was no statistically significant change in either the total number of antibiotic prescriptions or expenditures associated with the policy of limiting their use. Conclusions: Although no direct cause and effect can be shown with these observational data, the results suggest that the change in reimbursement policy to restrict prescribing of fluoroquinolones decreased their use and associated expenditures. These decreases were offset by increases in the use of other antibiotics. The balance of consequent benefit and harm of these shifts in prescribing patterns needs to be examined carefully. Alternative solutions to encourage appropriate use of antibiotics deserve exploration." @default.
- W2058671732 created "2016-06-24" @default.
- W2058671732 creator A5009264005 @default.
- W2058671732 creator A5014346677 @default.
- W2058671732 creator A5049401142 @default.
- W2058671732 creator A5051317639 @default.
- W2058671732 creator A5067616357 @default.
- W2058671732 creator A5075116351 @default.
- W2058671732 creator A5076401053 @default.
- W2058671732 creator A5091039176 @default.
- W2058671732 date "2006-01-01" @default.
- W2058671732 modified "2023-10-01" @default.
- W2058671732 title "Impact of administrative restrictions on antibiotic use and expenditure in Ontario: time series analysis" @default.
- W2058671732 doi "https://doi.org/10.1258/135581906775094253" @default.
- W2058671732 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16378528" @default.
- W2058671732 hasPublicationYear "2006" @default.
- W2058671732 type Work @default.
- W2058671732 sameAs 2058671732 @default.
- W2058671732 citedByCount "25" @default.
- W2058671732 countsByYear W20586717322012 @default.
- W2058671732 countsByYear W20586717322014 @default.
- W2058671732 countsByYear W20586717322019 @default.
- W2058671732 countsByYear W20586717322021 @default.
- W2058671732 countsByYear W20586717322023 @default.
- W2058671732 crossrefType "journal-article" @default.
- W2058671732 hasAuthorship W2058671732A5009264005 @default.
- W2058671732 hasAuthorship W2058671732A5014346677 @default.
- W2058671732 hasAuthorship W2058671732A5049401142 @default.
- W2058671732 hasAuthorship W2058671732A5051317639 @default.
- W2058671732 hasAuthorship W2058671732A5067616357 @default.
- W2058671732 hasAuthorship W2058671732A5075116351 @default.
- W2058671732 hasAuthorship W2058671732A5076401053 @default.
- W2058671732 hasAuthorship W2058671732A5091039176 @default.
- W2058671732 hasConcept C10138342 @default.
- W2058671732 hasConcept C109168655 @default.
- W2058671732 hasConcept C126322002 @default.
- W2058671732 hasConcept C144133560 @default.
- W2058671732 hasConcept C160735492 @default.
- W2058671732 hasConcept C162324750 @default.
- W2058671732 hasConcept C187212893 @default.
- W2058671732 hasConcept C23131810 @default.
- W2058671732 hasConcept C2426938 @default.
- W2058671732 hasConcept C2776865356 @default.
- W2058671732 hasConcept C2777629877 @default.
- W2058671732 hasConcept C2778512257 @default.
- W2058671732 hasConcept C2779703844 @default.
- W2058671732 hasConcept C501593827 @default.
- W2058671732 hasConcept C50522688 @default.
- W2058671732 hasConcept C71924100 @default.
- W2058671732 hasConcept C86803240 @default.
- W2058671732 hasConcept C89423630 @default.
- W2058671732 hasConcept C98274493 @default.
- W2058671732 hasConceptScore W2058671732C10138342 @default.
- W2058671732 hasConceptScore W2058671732C109168655 @default.
- W2058671732 hasConceptScore W2058671732C126322002 @default.
- W2058671732 hasConceptScore W2058671732C144133560 @default.
- W2058671732 hasConceptScore W2058671732C160735492 @default.
- W2058671732 hasConceptScore W2058671732C162324750 @default.
- W2058671732 hasConceptScore W2058671732C187212893 @default.
- W2058671732 hasConceptScore W2058671732C23131810 @default.
- W2058671732 hasConceptScore W2058671732C2426938 @default.
- W2058671732 hasConceptScore W2058671732C2776865356 @default.
- W2058671732 hasConceptScore W2058671732C2777629877 @default.
- W2058671732 hasConceptScore W2058671732C2778512257 @default.
- W2058671732 hasConceptScore W2058671732C2779703844 @default.
- W2058671732 hasConceptScore W2058671732C501593827 @default.
- W2058671732 hasConceptScore W2058671732C50522688 @default.
- W2058671732 hasConceptScore W2058671732C71924100 @default.
- W2058671732 hasConceptScore W2058671732C86803240 @default.
- W2058671732 hasConceptScore W2058671732C89423630 @default.
- W2058671732 hasConceptScore W2058671732C98274493 @default.
- W2058671732 hasIssue "1" @default.
- W2058671732 hasLocation W20586717321 @default.
- W2058671732 hasLocation W20586717322 @default.
- W2058671732 hasOpenAccess W2058671732 @default.
- W2058671732 hasPrimaryLocation W20586717321 @default.
- W2058671732 hasRelatedWork W1953125156 @default.
- W2058671732 hasRelatedWork W2119853342 @default.
- W2058671732 hasRelatedWork W2121619948 @default.
- W2058671732 hasRelatedWork W2191730108 @default.
- W2058671732 hasRelatedWork W2286943257 @default.
- W2058671732 hasRelatedWork W2916045875 @default.
- W2058671732 hasRelatedWork W3009141905 @default.
- W2058671732 hasRelatedWork W3181093099 @default.
- W2058671732 hasRelatedWork W4380630403 @default.
- W2058671732 hasRelatedWork W2519764742 @default.
- W2058671732 hasVolume "11" @default.
- W2058671732 isParatext "false" @default.
- W2058671732 isRetracted "false" @default.
- W2058671732 magId "2058671732" @default.
- W2058671732 workType "article" @default.