Matches in SemOpenAlex for { <https://semopenalex.org/work/W2058703458> ?p ?o ?g. }
- W2058703458 endingPage "175" @default.
- W2058703458 startingPage "166" @default.
- W2058703458 abstract "The responses to vancomycin and 11 other antibacterial drugs and the nutritional requirements of gonococci recovered from two selective media were determined. Single urogenital specimens from 508 patients attending a social hygiene clinic in 1975 yielded 97 strains of Neisseria gonorrhoeae; 95 were recovered on VCNT (a modification of Thayer-Martin medium), always inoculated first, and 69 on LC medium containing lincomycin (4 micrograms/ml) and colistin (5 micrograms/ml). The two drugs at these concentrations in LC medium were not inhibitory for isolates from either medium. Unexpectedly, three isolates on VCNT were susceptible to vancomycin at the concentrations (3 micrograms/ml) in VCNT medium; these three were typically sensitive to penicillins but were hypersusceptible to erythromycin (inhibited by less than or greater than 0.05 micrograms/ml) and rifampin (less than or equal to 0.02 micrograms/ml). Resistance to streptomycin (greater than or equal to 500 micrograms/ml) (22% of the strains) was correlated with increased resistance to penicillins, erythromycin, and rifampin in most instances. All streptomycin-resistant gonococci required proline, or arginine, or none of the test compounds. Strains requiring arginine, hypoxanthine, and uracil were uniformly sensitive to antibiotics but not hypersusceptible. In contrast, six strains of N gonorrhoeae isolated in Denmark required arginine (not satisfied by ornithine), hypoxanthine, and uracil and were hypersusceptible to vancomycin (inhibited by 0.5 micrograms/ml), erythromycin, and rifampin. DNA-mediated transformation showed that all three hypersusceptibilities of one Danish strain were introduced together into a wild-type gonococcus, suggesting that a mutation of an env (envelope) locus might be responsible for the atypical permeability." @default.
- W2058703458 created "2016-06-24" @default.
- W2058703458 creator A5016183087 @default.
- W2058703458 creator A5017600412 @default.
- W2058703458 creator A5065774021 @default.
- W2058703458 creator A5070433972 @default.
- W2058703458 date "1982-06-01" @default.
- W2058703458 modified "2023-09-25" @default.
- W2058703458 title "Auxotypes and antibacterial resistance to gonococci with differing susceptibilities to vancomycin." @default.
- W2058703458 cites W1429514284 @default.
- W2058703458 cites W1561404976 @default.
- W2058703458 cites W164381428 @default.
- W2058703458 cites W1905464221 @default.
- W2058703458 cites W1942649665 @default.
- W2058703458 cites W1972013569 @default.
- W2058703458 cites W1973189575 @default.
- W2058703458 cites W1986381954 @default.
- W2058703458 cites W1988497992 @default.
- W2058703458 cites W1993862242 @default.
- W2058703458 cites W1994466961 @default.
- W2058703458 cites W2004819787 @default.
- W2058703458 cites W2012298204 @default.
- W2058703458 cites W2013201971 @default.
- W2058703458 cites W2014218334 @default.
- W2058703458 cites W2015147110 @default.
- W2058703458 cites W2026556773 @default.
- W2058703458 cites W2029226424 @default.
- W2058703458 cites W2033893549 @default.
- W2058703458 cites W2047187166 @default.
- W2058703458 cites W2052451523 @default.
- W2058703458 cites W2055592016 @default.
- W2058703458 cites W2065575460 @default.
- W2058703458 cites W2083566256 @default.
- W2058703458 cites W2084543034 @default.
- W2058703458 cites W2086127782 @default.
- W2058703458 cites W2090977415 @default.
- W2058703458 cites W2091531502 @default.
- W2058703458 cites W2098299629 @default.
- W2058703458 cites W2133349057 @default.
- W2058703458 cites W2147123765 @default.
- W2058703458 cites W2169510914 @default.
- W2058703458 cites W2170097444 @default.
- W2058703458 cites W2263273202 @default.
- W2058703458 cites W2277755278 @default.
- W2058703458 cites W2320464941 @default.
- W2058703458 cites W2329011810 @default.
- W2058703458 cites W23416709 @default.
- W2058703458 cites W2394650094 @default.
- W2058703458 cites W2412920270 @default.
- W2058703458 cites W4252793646 @default.
- W2058703458 doi "https://doi.org/10.1136/sti.58.3.166" @default.
- W2058703458 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1046038" @default.
- W2058703458 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6805849" @default.
- W2058703458 hasPublicationYear "1982" @default.
- W2058703458 type Work @default.
- W2058703458 sameAs 2058703458 @default.
- W2058703458 citedByCount "4" @default.
- W2058703458 crossrefType "journal-article" @default.
- W2058703458 hasAuthorship W2058703458A5016183087 @default.
- W2058703458 hasAuthorship W2058703458A5017600412 @default.
- W2058703458 hasAuthorship W2058703458A5065774021 @default.
- W2058703458 hasAuthorship W2058703458A5070433972 @default.
- W2058703458 hasBestOaLocation W20587034581 @default.
- W2058703458 hasConcept C176947019 @default.
- W2058703458 hasConcept C2775843808 @default.
- W2058703458 hasConcept C2778980435 @default.
- W2058703458 hasConcept C2779166590 @default.
- W2058703458 hasConcept C2779259085 @default.
- W2058703458 hasConcept C2779489039 @default.
- W2058703458 hasConcept C2780206985 @default.
- W2058703458 hasConcept C2780923616 @default.
- W2058703458 hasConcept C501593827 @default.
- W2058703458 hasConcept C523546767 @default.
- W2058703458 hasConcept C54355233 @default.
- W2058703458 hasConcept C71924100 @default.
- W2058703458 hasConcept C86803240 @default.
- W2058703458 hasConcept C89423630 @default.
- W2058703458 hasConceptScore W2058703458C176947019 @default.
- W2058703458 hasConceptScore W2058703458C2775843808 @default.
- W2058703458 hasConceptScore W2058703458C2778980435 @default.
- W2058703458 hasConceptScore W2058703458C2779166590 @default.
- W2058703458 hasConceptScore W2058703458C2779259085 @default.
- W2058703458 hasConceptScore W2058703458C2779489039 @default.
- W2058703458 hasConceptScore W2058703458C2780206985 @default.
- W2058703458 hasConceptScore W2058703458C2780923616 @default.
- W2058703458 hasConceptScore W2058703458C501593827 @default.
- W2058703458 hasConceptScore W2058703458C523546767 @default.
- W2058703458 hasConceptScore W2058703458C54355233 @default.
- W2058703458 hasConceptScore W2058703458C71924100 @default.
- W2058703458 hasConceptScore W2058703458C86803240 @default.
- W2058703458 hasConceptScore W2058703458C89423630 @default.
- W2058703458 hasIssue "3" @default.
- W2058703458 hasLocation W20587034581 @default.
- W2058703458 hasLocation W20587034582 @default.
- W2058703458 hasLocation W20587034583 @default.
- W2058703458 hasLocation W20587034584 @default.
- W2058703458 hasOpenAccess W2058703458 @default.
- W2058703458 hasPrimaryLocation W20587034581 @default.